Literature DB >> 20163679

Evaluation [corrected] of transgenic event CBH 351 (StarLink) corn in pig.

Chisato Yonemochi1, Keisei Suga, Chisato Harada, Michito Hanazumi.   

Abstract

This study examined the influence of transgenic event CBH (StarLink; SL)-derived hybrid corn on growth, health and physiological functions of pigs, as well as the possibility of transferring the cry9C gene or Cry9C protein to the blood, liver or muscles, in comparison with pigs fed a diet with non-transgenic (isogenic) corn (non-SL). The diet for the SL group was composed of 70% SL corn, and the diet for the non-SL group was composed of 70% non-SL corn. Forty pigs approximately 3 months in age were used in the current experiment. After the pigs were acclimatized to their environment for 7 days, they were fed piglet diets for 7 weeks, and afterwards fed growing-finishing diets until the end of the experiment. There were no significant differences in bodyweight gain, feed intake or feed conversion ratio between the pigs fed SL diet and those of non-SL diet. No abnormalities were observed in the health conditions of either the SL or the non-SL group. Moreover, no significant differences were observed between the two groups in hematological values, histopathological examination and necropsy findings. Although the serum biochemical values within each group were normal, the blood urea nitrogen values of the SL group showed a tendency to be slightly higher than those of the non-SL group. Also, the blood glucose values of the SL group were significantly lower than those of the non-SL group. However, the cause of the significant differences in the blood glucose values between the two groups is unknown. The PCR and ELISA did not detect the cry9C gene and Cry9C protein in the blood, liver or muscles of the pigs at the end of the experiment.

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Year:  2010        PMID: 20163679     DOI: 10.1111/j.1740-0929.2009.00718.x

Source DB:  PubMed          Journal:  Anim Sci J        ISSN: 1344-3941            Impact factor:   1.749


  5 in total

1.  Fate of transgenic DNA from orally administered Bt MON810 maize and effects on immune response and growth in pigs.

Authors:  Maria C Walsh; Stefan G Buzoianu; Gillian E Gardiner; Mary C Rea; Eva Gelencsér; Anna Jánosi; Michelle M Epstein; R Paul Ross; Peadar G Lawlor
Journal:  PLoS One       Date:  2011-11-23       Impact factor: 3.240

2.  Horizontal gene transfer from genetically modified plants - Regulatory considerations.

Authors:  Joshua G Philips; Elena Martin-Avila; Andrea V Robold
Journal:  Front Bioeng Biotechnol       Date:  2022-08-31

3.  Detection of transgenic and endogenous plant DNA fragments and proteins in the digesta, blood, tissues, and eggs of laying hens fed with phytase transgenic corn.

Authors:  Qiugang Ma; Chunqi Gao; Jianyun Zhang; Lihong Zhao; Wenbo Hao; Cheng Ji
Journal:  PLoS One       Date:  2013-04-08       Impact factor: 3.240

4.  Effects of feeding Bt MON810 maize to pigs for 110 days on peripheral immune response and digestive fate of the cry1Ab gene and truncated Bt toxin.

Authors:  Maria C Walsh; Stefan G Buzoianu; Mary C Rea; Orla O'Donovan; Eva Gelencsér; Gabriella Ujhelyi; R Paul Ross; Gillian E Gardiner; Peadar G Lawlor
Journal:  PLoS One       Date:  2012-05-04       Impact factor: 3.240

Review 5.  The use of whole food animal studies in the safety assessment of genetically modified crops: limitations and recommendations.

Authors:  Andrew Bartholomaeus; Wayne Parrott; Genevieve Bondy; Kate Walker
Journal:  Crit Rev Toxicol       Date:  2013-11       Impact factor: 5.635

  5 in total

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