Literature DB >> 20162420

Effects of bioflavonoids in the management of subclinical varicocele.

Nicola Zampieri1, Maristella Pellegrino, Alberto Ottolenghi, Francesco Saverio Camoglio.   

Abstract

BACKGROUND: Subclinical varicocele is a relative rare condition. The aim of this study is to identify the role of bioflavonoids in the management of subclinical varicocele.
MATERIALS AND METHODS: We analyzed the medical charts of patients treated for subclinical varicocele with bioflavonoids between 1999 and 2004; inclusion criteria were created before treatment. Short and long-term results after treatment were studied and compared with untreated patients.
RESULTS: One hundred and sixty-eight patients with left subclinical varicocele were included in the study. Long-term results showed a possible correlation between use of bioflavonoids and lesser rate of clinical progression to palpable varicocele (11 vs. 31%), higher rate of stable vein reflux (47 vs. 38%) and higher resolution rate (41 vs. 31%) (p > 0.05). Bioflavonoids did not show any protective factor against testicular growth arrest.
CONCLUSIONS: Subclinical varicocele should be considered as the starting point of varicocele, and although the use of bioflavonoids in patients with subclinical varicocele could reduce the development of palpable varicocele, it cannot prevent the onset of testicular growth arrest.

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Year:  2010        PMID: 20162420     DOI: 10.1007/s00383-010-2574-9

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  16 in total

1.  Varicocele size and results of varicocelectomy in selected subfertile men with varicocele.

Authors:  L Dubin; R D Amelar
Journal:  Fertil Steril       Date:  1970-08       Impact factor: 7.329

2.  Effects of micronised purified flavonoid fraction on pain, spermiogram and scrotal color Doppler parameters in patients with painful varicocele.

Authors:  Süleyman Kiliç; Ali Güneş; Deniz Ipek; Abdurrahim Dusak; Gülsen Güneş; Mevlana Derya Balbay; Yaşar Can Baydinç
Journal:  Urol Int       Date:  2005       Impact factor: 2.089

3.  Reporting standards in venous disease: an update. International Consensus Committee on Chronic Venous Disease.

Authors:  J M Porter; G L Moneta
Journal:  J Vasc Surg       Date:  1995-04       Impact factor: 4.268

4.  The effect of varicocele repair on testicular volume in children and adolescents with varicocele.

Authors:  Selahitten Cayan; Erdem Akbay; Murat Bozlu; Erdal Doruk; Erim Erdem; Deniz Acar; Ercüment Ulusoy
Journal:  J Urol       Date:  2002-08       Impact factor: 7.450

5.  Bilateral but not unilateral testicular hypotrophy predicts for severe impairment of semen quality in men with varicocele undergoing infertility evaluation.

Authors:  Alex K Wu; Thomas J Walsh; Surat Phonsombat; Mary S Croughan; Paul J Turek
Journal:  Urology       Date:  2008-06       Impact factor: 2.649

6.  Relationship between varicocele grade, vein reflux and testicular growth arrest.

Authors:  Nicola Zampieri; Veronica Zuin; Michele Corroppolo; Alberto Ottolenghi; Francesco Saverio Camoglio
Journal:  Pediatr Surg Int       Date:  2008-04-18       Impact factor: 1.827

7.  Longitudinal study of semen quality in adolescents with varicocele: to treat or not?

Authors:  Nicola Zampieri; Michele Corroppolo; Veronica Zuin; Raimondo Maximillian Cervellione; Alberto Ottolenghi; Francesco Saverio Camoglio
Journal:  Urology       Date:  2007-11       Impact factor: 2.649

8.  The Doppler assessment of varicoceles and internal spermatic vein reflux in infertile men.

Authors:  A V Hirsh; K M Cameron; J P Tyler; J Simpson; J P Pryor
Journal:  Br J Urol       Date:  1980-02

9.  Seminal improvement following repair of ultrasound detected subclinical varicoceles.

Authors:  J P Jarow; S R Ogle; L A Eskew
Journal:  J Urol       Date:  1996-04       Impact factor: 7.450

10.  Relationship between testicular volume and varicocele in patients with infertility.

Authors:  Hideo Sakamoto; Yoshio Ogawa; Hideki Yoshida
Journal:  Urology       Date:  2008-01       Impact factor: 2.649

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  5 in total

Review 1.  Insight into oxidative stress in varicocele-associated male infertility: part 2.

Authors:  Alaa Hamada; Sandro C Esteves; Ashok Agarwal
Journal:  Nat Rev Urol       Date:  2012-11-20       Impact factor: 14.432

2.  Effects of micronised purified flavonoid fraction on pain, semen analysis and scrotal color Doppler parameters in patients with painful varicocele; results of a randomized placebo-controlled study.

Authors:  Haluk Söylemez; Süleyman Kiliç; Murat Atar; Necmettin Penbegül; Ahmet Ali Sancaktutar; Yaşar Bozkurt
Journal:  Int Urol Nephrol       Date:  2011-07-30       Impact factor: 2.370

3.  Oxidative Stress and Varicocele-Associated Male Infertility.

Authors:  Terence Chun-Ting Lai; Shubhadeep Roychoudhury; Chak-Lam Cho
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 2.622

4.  The role of flaxseed and vitamin E on oxidative stress in prepubertal rats with experimental varicocele: An experimental study.

Authors:  Shahla Sohrabipour; Adele Jafari; Mohamad Kamalinejad; Abdolfatah Sarrafnejd; Taherah Shahrestany; Hamid-Reza Sadeghipour
Journal:  Iran J Reprod Med       Date:  2013-06

Review 5.  An update on the role of medical treatment including antioxidant therapy in varicocele.

Authors:  Harshit Garg; Rajeev Kumar
Journal:  Asian J Androl       Date:  2016 Mar-Apr       Impact factor: 3.285

  5 in total

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