| Literature DB >> 20162396 |
Nguyen Huu Tung1, Chau Van Minh, Phan Van Kiem, Hoang Thanh Huong, Tran Thu Ha, Nguyen Tien Dat, Nguyen Xuan Nhiem, Nguyen Xuan Cuong, Jae-Hee Hyun, Hee-Kyoung Kang, Young Ho Kim.
Abstract
One new C(29) sterol with a cyclopropane ring at C-25 and C-26, aragusteroketal B (1), and aragusterol B (2) were isolated from the Vietnamese marine sponge Ianthella sp. Their structures were elucidated by extensive spectroscopic analyses. Both 1 and 2 showed moderate cytotoxic activity against MCF-7, SK-Hep-1, and HeLa cell lines with IC(50) in the range of 12.8-27.8 microM.Entities:
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Year: 2010 PMID： 20162396 DOI： 10.1007/s12272-009-2205-y
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946