In order to investigate the relationship between depth within membranes of singlet oxygen generation and effectiveness of photodynamic therapy of tumors, analogs of protoporphyrin-IX 1 bearing five 4 and seven 5 carbon atoms (in place of the 3-carbon atom chain in 1) were synthesized from monopyrrole precursors.
In order to investigate the relationship between depth within membranes of singlet oxygen generation and effectiveness of photodynamic therapy of n class="Disease">tumors, analogs of protoporphyrin-IX 1 bearing five 4 and seven 5 carbon atoms (in place of the 3-carbon atom chain in 1) were synthesized from monopyrrole precursors.
Authors: Irena Bronshteint; Svetlana Aulova; Asta Juzeniene; Vladimir Iani; Li-Wei Ma; Kevin M Smith; Zvi Malik; Johan Moan; Benjamin Ehrenberg Journal: Photochem Photobiol Date: 2006 Sep-Oct Impact factor: 3.421
Authors: Irena Bronshtein; Michal Afri; Hana Weitman; Aryeh A Frimer; Kevin M Smith; Benjamin Ehrenberg Journal: Biophys J Date: 2004-08 Impact factor: 4.033