Literature DB >> 20161404

Syntheses of protoporphyrin-IX derivatives bearing extended propionate side-chains.

Robert T Holmes, Jianming Lu, Celinah Mwakwari, Kevin M Smith.   

Abstract

In order to investigate the relationship between depth within membranes of singlet oxygen generation and effectiveness of photodynamic therapy of tumors, analogs of protoporphyrin-IX 1 bearing five 4 and seven 5 carbon atoms (in place of the 3-carbon atom chain in 1) were synthesized from monopyrrole precursors.

Entities:  

Year:  2009        PMID： 20161404      PMCID： PMC2783647          DOI： 10.1901/jaba.2009.2010-5

Source DB:  PubMed          Journal:  ARKIVOC            Impact factor:   1.140


  11 in total

1.  The depth of porphyrin in a membrane and the membrane's physical properties affect the photosensitizing efficiency.

Authors:  Adina Lavi; Hana Weitman; Robert T Holmes; Kevin M Smith; Benjamin Ehrenberg
Journal:  Biophys J       Date:  2002-04       Impact factor: 4.033

2.  Plasma membrane depolarization and calcium influx during cell injury by photodynamic action.

Authors:  K G Specht; M A Rodgers
Journal:  Biochim Biophys Acta       Date:  1991-11-18

Review 3.  Lysosomes and microtubules as targets for photochemotherapy of cancer.

Authors:  K Berg; J Moan
Journal:  Photochem Photobiol       Date:  1997-03       Impact factor: 3.421

4.  Pyrroles and related compounds. 33. Total synthesis of deuteriated derivatives of protoporphyrin-IX for nuclear magnetic resonance studies of haemoproteins.

Authors:  J A Cavaleiro; A M Rocha Gonsalves; G W Kenner; K M Smith
Journal:  J Chem Soc Perkin 1       Date:  1974

Review 5.  Structure and mechanism of haemoglobin.

Authors:  M F Perutz
Journal:  Br Med Bull       Date:  1976-09       Impact factor: 4.291

6.  The effect of pH on the topography of porphyrins in lipid membranes.

Authors:  Irena Bronshtein; Kevin M Smith; Benjamin Ehrenberg
Journal:  Photochem Photobiol       Date:  2005 Mar-Apr       Impact factor: 3.421

7.  In vitro and in vivo photosensitization by protoporphyrins possessing different lipophilicities and vertical localization in the membrane.

Authors:  Irena Bronshteint; Svetlana Aulova; Asta Juzeniene; Vladimir Iani; Li-Wei Ma; Kevin M Smith; Zvi Malik; Johan Moan; Benjamin Ehrenberg
Journal:  Photochem Photobiol       Date:  2006 Sep-Oct       Impact factor: 3.421

8.  Kinetics and yield of singlet oxygen photosensitized by hypericin in organic and biological media.

Authors:  B Ehrenberg; J L Anderson; C S Foote
Journal:  Photochem Photobiol       Date:  1998-08       Impact factor: 3.421

9.  Do liposome-binding constants of porphyrins correlate with their measured and predicted partitioning between octanol and water?

Authors:  Mariusz Kepczyński; Ramasamy P Pandian; Kevin M Smith; Benjamin Ehrenberg
Journal:  Photochem Photobiol       Date:  2002-08       Impact factor: 3.421

10.  Porphyrin depth in lipid bilayers as determined by iodide and parallax fluorescence quenching methods and its effect on photosensitizing efficiency.

Authors:  Irena Bronshtein; Michal Afri; Hana Weitman; Aryeh A Frimer; Kevin M Smith; Benjamin Ehrenberg
Journal:  Biophys J       Date:  2004-08       Impact factor: 4.033
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  1 in total

Review 1.  The Red Color of Life Transformed - Synthetic Advances and Emerging Applications of Protoporphyrin IX in Chemical Biology.

Authors:  Elisabeth Sitte; Mathias O Senge
Journal:  European J Org Chem       Date:  2020-03-30
  1 in total

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