Literature DB >> 20160002

Kidney and urinary tract imaging: triple-bolus multidetector CT urography as a one-stop shop--protocol design, opacification, and image quality analysis.

Maka Kekelidze1, Roy S Dwarkasing, Marcel L Dijkshoorn, Karolina Sikorska, Paul C M S Verhagen, Gabriel P Krestin.   

Abstract

PURPOSE: To retrospectively evaluate renal, vascular, and urinary tract visualization following a single postcontrast multidetector computed tomographic (CT) urographic sequence performed with three limited-volume bolus injections.
MATERIALS AND METHODS: The institutional review board approved this retrospective study. Patient informed consent was waived. Triple-bolus multidetector CT urography was performed in 110 patients. Triple-bolus protocol consisted of 30 mL of contrast material at 2 mL/sec at 0 seconds, 50 mL at 1.5 mL/sec at 435 seconds, 65 mL at 3 mL/sec at 488 seconds, with total abdominal scanning time of 510 seconds. Two independent readers rated urinary tract opacification and qualitatively and quantitatively assessed renal parenchymal and vascular contrast enhancement. Upper urinary tract (UUT) distention was measured by one reader. Interobserver agreement was assessed by using kappa statistics.
RESULTS: Complete opacification of the intrarenal collecting system and proximal ureter was achieved in 91% (184 of 202) (kappa = 0.62) and 82% (166 of 202) (kappa = 0.94) of segments, respectively. The distal ureter was not opacified in 21% of the cases (kappa = 0.92), and the bladder was not opacified in 20% of the cases. Mean distention was higher for proximal (3.9 mm) than for distal (3.7 mm) segments. Image quality of renal parenchymal enhancement was excellent in 76% of cases. Arteries showed better contrast enhancement than veins (excellent rating in 89% vs 59% of the cases). Radiation dose calculated for triple-bolus acquisition was 9.8 mSv.
CONCLUSION: Triple-bolus multidetector CT urography is a dose-efficient protocol acquiring corticomedullary-nephrographic-excretory and vascular enhancement phases in a single acquisition and provides sufficient opacification and distention of the UUT. Simultaneously, adequate image quality of renal parenchyma and vascular anatomy is achieved.

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Year:  2010        PMID: 20160002     DOI: 10.1148/radiol.09082074

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  25 in total

1.  Current status of low dose multi-detector CT in the urinary tract.

Authors:  Mi Kim Sung; Sarabjeet Singh; Mannudeep K Kalra
Journal:  World J Radiol       Date:  2011-11-28

Review 2.  [Strategies for reducing the CT radiation dose].

Authors:  S T Schindera; C Nauer; R Treier; P Trueb; G von Allmen; P Vock; Z Szucs-Farkas
Journal:  Radiologe       Date:  2010-12       Impact factor: 0.635

3.  Model-based Multi-material Decomposition using Spatial-Spectral CT Filters.

Authors:  J Webster Stayman; Steven Tilley
Journal:  Conf Proc Int Conf Image Form Xray Comput Tomogr       Date:  2018-05

4.  Urinary stone detection and characterisation with dual-energy CT urography after furosemide intravenous injection: preliminary results.

Authors:  Diomidis Botsikas; Catrina Hansen; Salvatore Stefanelli; Christoph D Becker; Xavier Montet
Journal:  Eur Radiol       Date:  2013-10-02       Impact factor: 5.315

5.  An education and training programme for radiological institutes: impact on the reduction of the CT radiation dose.

Authors:  Sebastian T Schindera; Reto Treier; Gabriel von Allmen; Claude Nauer; Philipp R Trueb; Peter Vock; Zsolt Szucs-Farkas
Journal:  Eur Radiol       Date:  2011-05-31       Impact factor: 5.315

Review 6.  Newer CT applications and their alternatives: what is appropriate in children?

Authors:  R Paul Guillerman
Journal:  Pediatr Radiol       Date:  2011-08-17

7.  64-Slice CT urography: optimisation of radiation dose.

Authors:  P Martingano; F Stacul; M F Cavallaro; S Cernic; P Bregant; M A Cova
Journal:  Radiol Med       Date:  2011-01-12       Impact factor: 3.469

8.  Photon-counting CT for simultaneous imaging of multiple contrast agents in the abdomen: An in vivo study.

Authors:  Rolf Symons; Bernhard Krauss; Pooyan Sahbaee; Tyler E Cork; Manu N Lakshmanan; David A Bluemke; Amir Pourmorteza
Journal:  Med Phys       Date:  2017-08-20       Impact factor: 4.071

9.  [Current strategies for dosage reduction in computed tomography].

Authors:  M S May; W Wuest; M M Lell; M Uder; W A Kalender; B Schmidt
Journal:  Radiologe       Date:  2012-10       Impact factor: 0.635

Review 10.  CT urography for hematuria.

Authors:  Nigel C Cowan
Journal:  Nat Rev Urol       Date:  2012-03-13       Impact factor: 14.432

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