Literature DB >> 20159672

Unexpected gamma glutamyltransferase rise increase during levetiracetam monotherapy.

Marcella Broli1, Federica Provini, Ilaria Naldi, Francesca Bisulli, Claudia Sama, Agostino Baruzzi, Paolo Tinuper, Roberto Riva.   

Abstract

Levetiracetam is an antiepileptic drug (AED) with a favourable tolerability profile with little or no effect on liver function. We describe an epileptic patient who developed a significant increase in gamma glutamyltransferase (gammaGT) while on levetiracetam monotherapy.

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Year:  2010        PMID： 20159672     DOI： 10.1684/epd.2010.0291

Source DB:  PubMed          Journal:  Epileptic Disord        ISSN： 1294-9361            Impact factor:   1.819


  6 in total

1.  Levetiracetam associated acute hepatic failure requiring liver transplantation: case report.

Authors:  Vithyalakshmi Selvaraj; Jayakrishna S Madabushi; Palanikumar Gunasekar; Sanjay P Singh
Journal:  J Neurol       Date:  2016-02-22       Impact factor: 4.849

2.  Acute liver failure associated with levetiracetam and lacosamide combination treatment for unspecified epileptic disorder.

Authors:  Ylse Gutiérrez-Grobe; Jose Antonio Bahena-Gonzalez; Magali Herrera-Gomar; Pedro Mendoza-Diaz; Sandra García-López; Octavio González-Chon
Journal:  Case Rep Emerg Med       Date:  2013-08-20

3.  Levetiracetam for epilepsy: an evidence map of efficacy, safety and economic profiles.

Authors:  Zhan-Miao Yi; Cheng Wen; Ting Cai; Lu Xu; Xu-Li Zhong; Si-Yan Zhan; Suo-Di Zhai
Journal:  Neuropsychiatr Dis Treat       Date:  2018-12-17       Impact factor: 2.570

4.  Assessment of the biomarkers of hepatotoxicity following carbamazepine, levetiracetam, and carbamazepine-levetiracetam adjunctive treatment in male Wistar rats.

Authors:  Opeyemi Samson Osuntokun; Ademola Adeniyi Babatunde; Gbola Olayiwola; Tope Gafar Atere; Olayemi Olutobi Oladokun; Kabiru Isola Adedokun
Journal:  Toxicol Rep       Date:  2021-03-10

5.  Effect of Levetiracetam Monotherapy on Liver Enzymes and Creatine Kinase Concentrations in Children with Epilepsy: A Prospective Study.

Authors:  Achilleas Attilakos; Argirios Dinopoulos; Maria Paschalidou; Maria Tsirouda; Alexia Prasouli; Nikos Siafakas; Anastasia Garoufi
Journal:  J Clin Neurol       Date:  2018-10       Impact factor: 3.077

6.  A Rare Case of Drug-Induced Liver Injury Caused by Levetiracetam.

Authors:  Tomohiro Kawaguchi; Teiji Tominaga
Journal:  Asian J Neurosurg       Date:  2019 Jul-Sep
  6 in total

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