| Literature DB >> 20159588 |
Alok Tomar1, David D Schlaepfer.
Abstract
Transmembrane growth factor and integrin matrix receptors form multiprotein signaling complexes with FAK, a cytoplasmic cell motility-associated kinase. In a recent issue of Molecular Cell, Long et al. now show that a PAK-phosphorylated alternate-spliced isoform of the steroid receptor coactivator-3 (SRC-3Delta4) bridges EGFR and FAK, enhancing breast carcinoma cell migration and metastasis. Copyright (c) 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20159588 PMCID： PMC3081666 DOI： 10.1016/j.devcel.2010.01.013
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270