| Literature DB >> 20159442 |
Abstract
The branching of dendrites and axons is a key determinant of neural circuit formation. In this issue of Neuron, Kawabe et al. demonstrate that the ubiquitin ligase Nedd4 promotes the branching of developing dendrites by targeting the small G protein Rap2. In a complementary study, Drinjakovic et al. show that Nedd4 promotes the branching of developing axons by ubiquitinating a different target, the phosphatase PTEN. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20159442 PMCID： PMC2825082 DOI： 10.1016/j.neuron.2010.01.028
Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173