Literature DB >> 201572

Chromosome banding, isoenzyme studies and determination of Epstein-Barr virus DNA content on human Burkitt lymphoma/mouse hybrids.

J Spira, S Povey, F Wiener, G Klein, M Andersson-Anvret.   

Abstract

Four independently fused hybrid clones derived from a cross between the mouse mammary carcinoma TA3Ha and the human Burkitt lymphoma line Daudi were tested for the EBV-determined nuclear antigen (EBNA), EBV-DNA and the presence of human chromosomes, in the course of serial propagation in vitro. EBNA and EBV-DNA were lost in parallel with the loss of human chromosomes. It seems that the persistence of EB-viral genetic information does not require the presence of a specific human chromosome(s) in this particular hybrid combination.

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Year:  1977        PMID： 201572     DOI： 10.1002/ijc.2910200605

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  2 in total

1.  Epstein-Barr virus and human chromosomes: close association of the resident viral genome and the expression of the virus-determined nuclear antigen (EBNA) with the presence of chromosome 14 in human-mouse hybrid cells.

Authors:  K Yamamoto; F Mizuno; T Matsuo; A Tanaka; M Nonoyama; T Osato
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

2.  Chromosome site for Epstein-Barr virus DNA in a Burkitt tumor cell line and in lymphocytes growth-transformed in vitro.

Authors:  A Henderson; S Ripley; M Heller; E Kieff
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205
  2 in total

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