Literature DB >> 20153976

HIV-1 elite controllers: beware of super-infections.

Olivier Clerc1, Sara Colombo, Sabine Yerly, Amalio Telenti, Matthias Cavassini.   

Abstract

Super- and co-infection with HIV-1 are generally associated with accelerated disease progression. We report on the outcome of super-infection in two HIV-1 infected individuals previously known as elite controllers. Both presented an acute retroviral syndrome following super-infection and showed an immuno-virological progression thereafter. Host genotyping failed to reveal any of the currently recognized protective factors associated with slow disease progression. This report indicates that elite controllers should be informed of the risk of super-infection, and illustrates the complexity of mounting broad anti-HIV immunity. Copyright 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 20153976     DOI： 10.1016/j.jcv.2010.01.013

Source DB:  PubMed          Journal:  J Clin Virol        ISSN： 1386-6532            Impact factor:   3.168


  12 in total

1.  HIV-1 continues to replicate and evolve in patients with natural control of HIV infection.

Authors:  Helene Mens; Mary Kearney; Ann Wiegand; Wei Shao; Kristian Schønning; Jan Gerstoft; Niels Obel; Frank Maldarelli; John W Mellors; Thomas Benfield; John M Coffin
Journal:  J Virol       Date:  2010-10-06       Impact factor: 5.103

Review 2.  HIV-1 replicative fitness in elite controllers.

Authors:  Michael A Lobritz; Kara G Lassen; Eric J Arts
Journal:  Curr Opin HIV AIDS       Date:  2011-05       Impact factor: 4.283

3.  Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection.

Authors:  Adrian Schmid; Sara Gianella; Viktor von Wyl; Karin J Metzner; Alexandra U Scherrer; Barbara Niederöst; Claudia F Althaus; Philip Rieder; Christina Grube; Beda Joos; Rainer Weber; Marek Fischer; Huldrych F Günthard
Journal:  PLoS One       Date:  2010-10-12       Impact factor: 3.240

Review 4.  Frequency and implications of HIV superinfection.

Authors:  Andrew D Redd; Thomas C Quinn; Aaron A R Tobian
Journal:  Lancet Infect Dis       Date:  2013-05-31       Impact factor: 25.071

5.  Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller.

Authors:  María Pernas; Concepción Casado; Carolina Arcones; Anuska Llano; Víctor Sánchez-Merino; Beatriz Mothe; José L Vicario; Eulalia Grau; Lidia Ruiz; Jorge Sánchez; Amalio Telenti; Eloísa Yuste; Christian Brander; Cecilio López- Galíndez
Journal:  PLoS One       Date:  2012-02-24       Impact factor: 3.240

6.  Immunologic and Virologic Progression in HIV Controllers: The Role of Viral "Blips" and Immune Activation in the ANRS CO21 CODEX Study.

Authors:  Nicolas Noel; Nathalie Lerolle; Camille Lécuroux; Cécile Goujard; Alain Venet; Asier Saez-Cirion; Veronique Avettand-Fenoël; Laurence Meyer; Faroudy Boufassa; Olivier Lambotte
Journal:  PLoS One       Date:  2015-07-06       Impact factor: 3.240

7.  Analysis of HIV-1 protease gene reveals frequent multiple infections followed by recombination among drug treated individuals living in São Paulo and Santos, Brazil.

Authors:  Edsel Renata De Morais Nunes; Jean Paulo Zukurov; Juliana Terzi Maricato; Maria Cecília Araripe Sucupira; Ricardo Sobhie Diaz; Luíz Mário Ramos Janini
Journal:  PLoS One       Date:  2014-01-03       Impact factor: 3.240

8.  Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers.

Authors:  Fanny Chereau; Yoann Madec; Caroline Sabin; Niels Obel; Ezequiel Ruiz-Mateos; Georgios Chrysos; Sarah Fidler; Clara Lehmann; Robert Zangerle; Linda Wittkop; Peter Reiss; Osamah Hamouda; Vicente Estrada Perez; Manuel Leal; Amanda Mocroft; Patricia Garcia De Olalla; Adriana Ammassari; Antonella D'Arminio Monforte; Cristina Mussini; Ferran Segura; Antonella Castagna; Matthias Cavassini; Sophie Grabar; Philippe Morlat; Stéphane De Wit; Olivier Lambotte; Laurence Meyer
Journal:  PLoS One       Date:  2017-04-05       Impact factor: 3.240

9.  HIV-1 Dual Infected LTNP-EC Patients Developed an Unexpected Antibody Cross-Neutralizing Activity.

Authors:  Maria Pernas; Victor Sanchez-Merino; Concepcion Casado; Alberto Merino-Mansilla; Isabel Olivares; Eloisa Yuste; Cecilio Lopez-Galindez
Journal:  PLoS One       Date:  2015-08-10       Impact factor: 3.240

10.  Variable Effect of HIV Superinfection on Clinical Status: Insights From Mathematical Modeling.

Authors:  Ágnes Móréh; András Szilágyi; István Scheuring; Viktor Müller
Journal:  Front Microbiol       Date:  2018-07-23       Impact factor: 5.640
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