| Literature DB >> 20153871 |
B Jacobsen1, D Algermissen, D Schaudien, M Venner, S Herzog, E Wentz, M Hewicker-Trautwein, W Baumgärtner, C Herden.
Abstract
Borna disease (BD) was diagnosed in a 2-year-old male alpaca with a history of chronic suppressed sexual desire and acute stretching convulsions. Microscopical examination of the central nervous system revealed non-purulent meningoencephalitis with mononuclear perivascular cuffing. The diagnosis was confirmed by immunohistochemistry, in-situ hybridization, polymerase chain reaction (PCR) and sequencing of PCR products and alignment with known Borna disease virus sequences. Serological screening of the herd was performed. This is the first detailed report of naturally occurring BD in alpacas. Copyright 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20153871 DOI： 10.1016/j.jcpa.2010.01.009
Source DB: PubMed Journal: J Comp Pathol ISSN： 0021-9975 Impact factor: 1.311