Literature DB >> 20153856

Fertility preservation following torsion and severe ischemic injury of a solitary testis.

Daniel Y Woodruff1, Gregory Horwitz, John Weigel, Ajay K Nangia.   

Abstract

OBJECTIVE: To present a case of solitary testicular torsion and an adolescent faced with future hypogonadism and infertility.
DESIGN: Case report.
SETTING: University-affiliated teaching hospital. PATIENT(S): A 16-year-old male with solitary testicular torsion of >8 hours' duration. INTERVENTION(S): Immediate scrotal exploration, orchiopexy, and sperm cryopreservation. MAIN OUTCOME MEASURE(S): Maintenance of testosterone production and determination of preservation after detorsion of an ischemic testis. RESULT(S): Color flow Doppler ultrasound showed markedly decreased flow to solitary testis. A subjectively dead testis was seen upon scrotal exploration, with the decision to proceed with orchiopexy. Semen analysis of cryopreserved specimen 50 hours after onset of symptoms showed 1.4 mL, normal sperm concentration (89 million/mL), 67% motility, and 28% World Health Organization morphology. Normal levels of testosterone were found at 4 and 12 weeks after surgery. Testicular salvage with normal intratesticular blood flow was seen by ultrasound at 4 and 12 weeks after surgery. CONCLUSION(S): To our knowledge, this is the first reported case of testicular salvage after torsion of a solitary testicle with subsequent normal semen analysis and cryopreservation. This demonstrates the need to attempt salvage even in cases of subjectively dead testicle and the importance of offering expedient sperm cryopreservation in such cases. Copyright (c) 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2010        PMID: 20153856     DOI: 10.1016/j.fertnstert.2009.12.057

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  7 in total

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Authors:  Xiaoying Zhang; Faqing Lv; Jie Tang
Journal:  Int J Clin Exp Med       Date:  2015-05-15

2.  Guideline-based management of male infertility: Why do we need it?

Authors:  Landon W Trost; Ajay Nehra
Journal:  Indian J Urol       Date:  2011-01

Review 3.  Organ-Protective Effects of Red Wine Extract, Resveratrol, in Oxidative Stress-Mediated Reperfusion Injury.

Authors:  Fu-Chao Liu; Hsin-I Tsai; Huang-Ping Yu
Journal:  Oxid Med Cell Longev       Date:  2015-06-16       Impact factor: 6.543

4.  Fertility preservation after bilateral severe testicular trauma.

Authors:  Giovanni Liguori; Nicola Pavan; Gianluca d'Aloia; Stefano Bucci; Bernardino de Concilio; Giorgio Mazzon; Giangiacomo Ollandini; Carlo Trombetta
Journal:  Asian J Androl       Date:  2014 Jul-Aug       Impact factor: 3.285

5.  Surgical practice among pediatric surgeons and pediatric urologists in the Kingdom of Saudi Arabia for the management of suspected testicular torsion.

Authors:  Hamdi H Almaramhy
Journal:  Saudi Med J       Date:  2018-12       Impact factor: 1.484

6.  Long-term impact of testicular torsion and its salvage on semen parameters and gonadal function.

Authors:  Dharmender Aggarwal; Kalpesh Parmar; Aditya Prakash Sharma; Shantanu Tyagi; Santosh Kumar; Shrawan Kumar Singh; Swati Gupta
Journal:  Indian J Urol       Date:  2022-04-01

7.  Update on fertility preservation from the Barcelona International Society for Fertility Preservation-ESHRE-ASRM 2015 expert meeting: indications, results and future perspectives.

Authors:  Francisca Martinez
Journal:  Hum Reprod       Date:  2017-09-01       Impact factor: 6.918

  7 in total

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