| Literature DB >> 20153143 |
Anthony C Ruocco1, John D Medaglia, Jennifer R Tinker, Hasan Ayaz, Evan M Forman, Cory F Newman, J Michael Williams, Frank G Hillary, Steven M Platek, Banu Onaral, Douglas L Chute.
Abstract
Frontal systems dysfunction and abandonment fears represent central features of borderline personality disorder (BPD). BPD subjects (n=10) and matched non-psychiatric comparison subjects (n=10) completed a social-cognitive task with two confederates instructed to either include or exclude subjects from a circumscribed interaction. Evoked cerebral blood oxygenation in frontal cortex was measured using 16-channel functional near infrared spectroscopy. BPD subjects showed left medial prefrontal cortex hyperactivation during social exclusion suggesting potential dysfunction of frontolimbic circuitry. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20153143 DOI： 10.1016/j.pscychresns.2009.12.001
Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222