Literature DB >> 20153141

Genetic association study of KREMEN1 and DKK1 and schizophrenia in a Japanese population.

Branko Aleksic1, Itaru Kushima, Yoshihito Ito, Yukako Nakamura, Hiroshi Ujike, Michio Suzuki, Toshiya Inada, Ryota Hashimoto, Masatoshi Takeda, Nakao Iwata, Norio Ozaki.   

Abstract

The aim of the current study was to examine the association of KREMEN1 and DKK1, two wnt pathway-related genes with schizophrenia in Japanese subjects. We genotyped 16 common genetic variants within the aforementioned genes and examined their associations with schizophrenia. Results demonstrated that a common variant in the promoter region of KREMEN1 might modulate the risk of schizophrenia in the Japanese. However, further replication will be needed for conclusive interpretation of the effect of this locus on the pathogenesis of schizophrenia. Copyright (c) 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20153141     DOI: 10.1016/j.schres.2010.01.014

Source DB:  PubMed          Journal:  Schizophr Res        ISSN: 0920-9964            Impact factor:   4.939


  11 in total

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2.  High Mobility Group Protein 1 and Dickkopf-Related Protein 1 in Schizophrenia and Treatment-Resistant Schizophrenia: Associations With Interleukin-6, Symptom Domains, and Neurocognitive Impairments.

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Journal:  Schizophr Bull       Date:  2021-03-16       Impact factor: 9.306

3.  Common variants in MAGI2 gene are associated with increased risk for cognitive impairment in schizophrenic patients.

Authors:  Takayoshi Koide; Masahiro Banno; Branko Aleksic; Saori Yamashita; Tsutomu Kikuchi; Kunihiro Kohmura; Yasunori Adachi; Naoko Kawano; Itaru Kushima; Yukako Nakamura; Takashi Okada; Masashi Ikeda; Kazutaka Ohi; Yuka Yasuda; Ryota Hashimoto; Toshiya Inada; Hiroshi Ujike; Tetsuya Iidaka; Michio Suzuki; Masatoshi Takeda; Nakao Iwata; Norio Ozaki
Journal:  PLoS One       Date:  2012-05-23       Impact factor: 3.240

4.  Neurodevelopment in schizophrenia: the role of the wnt pathways.

Authors:  Isabella Panaccione; Flavia Napoletano; Alberto Maria Forte; Giorgio D Kotzalidis; Antonio Del Casale; Chiara Rapinesi; Chiara Brugnoli; Daniele Serata; Federica Caccia; Ilaria Cuomo; Elisa Ambrosi; Alessio Simonetti; Valeria Savoja; Lavinia De Chiara; Emanuela Danese; Giovanni Manfredi; Delfina Janiri; Marta Motolese; Ferdinando Nicoletti; Paolo Girardi; Gabriele Sani
Journal:  Curr Neuropharmacol       Date:  2013-09       Impact factor: 7.363

5.  Synaptic Wnt signaling-a contributor to major psychiatric disorders?

Authors:  Nathan D Okerlund; Benjamin N R Cheyette
Journal:  J Neurodev Disord       Date:  2011-04-28       Impact factor: 4.025

6.  A case control association study and cognitive function analysis of neuropilin and tolloid-like 1 gene and schizophrenia in the Japanese population.

Authors:  Masahiro Banno; Takayoshi Koide; Branko Aleksic; Kazuo Yamada; Tsutomu Kikuchi; Kunihiro Kohmura; Yasunori Adachi; Naoko Kawano; Itaru Kushima; Masashi Ikeda; Toshiya Inada; Takeo Yoshikawa; Nakao Iwata; Norio Ozaki
Journal:  PLoS One       Date:  2011-12-20       Impact factor: 3.240

7.  A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation.

Authors:  P-M Martin; X Yang; N Robin; E Lam; J S Rabinowitz; C A Erdman; J Quinn; L A Weiss; S P Hamilton; P-Y Kwok; R T Moon; B N R Cheyette
Journal:  Transl Psychiatry       Date:  2013-09-03       Impact factor: 6.222

8.  Wisconsin Card Sorting Test scores and clinical and sociodemographic correlates in Schizophrenia: multiple logistic regression analysis.

Authors:  Masahiro Banno; Takayoshi Koide; Branko Aleksic; Takashi Okada; Tsutomu Kikuchi; Kunihiro Kohmura; Yasunori Adachi; Naoko Kawano; Tetsuya Iidaka; Norio Ozaki
Journal:  BMJ Open       Date:  2012-11-06       Impact factor: 2.692

9.  Identifying rare and common disease associated variants in genomic data using Parkinson's disease as a model.

Authors:  Ying-Chao Lin; Ai-Ru Hsieh; Ching-Lin Hsiao; Shang-Jung Wu; Hui-Min Wang; Ie-Bin Lian; Cathy S J Fann
Journal:  J Biomed Sci       Date:  2014-08-30       Impact factor: 8.410

10.  Association study of BCL9 gene polymorphism rs583583 with schizophrenia and negative symptoms in Japanese population.

Authors:  Hiroki Kimura; Satoshi Tanaka; Itaru Kushima; Takayoshi Koide; Masahiro Banno; Tsutomu Kikuchi; Yukako Nakamura; Tomoko Shiino; Akira Yoshimi; Tomoko Oya-Ito; Jingrui Xing; Chenyao Wang; Yuto Takasaki; Branko Aleksic; Takashi Okada; Masashi Ikeda; Toshiya Inada; Tetsuya Iidaka; Nakao Iwata; Norio Ozaki
Journal:  Sci Rep       Date:  2015-10-23       Impact factor: 4.379

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