Literature DB >> 20152865

D2 antagonist during development decreases anxiety and infanticidal behavior in adult female prairie voles (Microtus ochrogaster).

Caroline M Hostetler1, Shanna L Harkey, Karen L Bales.   

Abstract

On postnatal day 8, prairie vole pups were randomly assigned a treatment of 1mg/kg SKF38393 (D1 agonist), quinpirole (D2 agonist), SCH23390 (D1 antagonist), eticlopride (D2 antagonist), or saline vehicle. As adults, females treated with eticlopride exhibited reduced anxiety-like behavior in an elevated plus maze and a reduction in infanticidal behavior. These behavioral effects were not seen in males. These data demonstrate that a single exposure to a D2 antagonist during development can have persistent, sex-specific effects on behavior into adulthood.

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Year:  2010        PMID： 20152865      PMCID： PMC3156575          DOI： 10.1016/j.bbr.2010.02.010

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN： 0166-4328            Impact factor:   3.332


  38 in total

1.  Postnatal development of the dopaminergic system of the striatum in the rat.

Authors:  J Antonopoulos; I Dori; A Dinopoulos; M Chiotelli; J G Parnavelas
Journal:  Neuroscience       Date:  2002       Impact factor: 3.590

2.  National trends in the outpatient treatment of children and adolescents with antipsychotic drugs.

Authors:  Mark Olfson; Carlos Blanco; Linxu Liu; Carmen Moreno; Gonzalo Laje
Journal:  Arch Gen Psychiatry       Date:  2006-06

3.  Developmental exposure to vasopressin increases aggression in adult prairie voles.

Authors:  J M Stribley; C S Carter
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

4.  Dopamine D2 receptors in the nucleus accumbens are important for social attachment in female prairie voles (Microtus ochrogaster).

Authors:  B Gingrich; Y Liu; C Cascio; Z Wang; T R Insel
Journal:  Behav Neurosci       Date:  2000-02       Impact factor: 1.912

5.  Effects of a partial D2-like receptor agonist on striatal dopamine autoreceptor functioning in preweanling rats.

Authors:  Shelly T Yoshida; Shelley A Baella; Nancy M Stuebner; Cynthia A Crawford; Sanders A McDougall
Journal:  Brain Res       Date:  2006-01-19       Impact factor: 3.252

6.  A critical role for nucleus accumbens dopamine in partner-preference formation in male prairie voles.

Authors:  Brandon J Aragona; Yan Liu; J Thomas Curtis; Friedrich K Stephan; Zuoxin Wang
Journal:  J Neurosci       Date:  2003-04-15       Impact factor: 6.167

7.  Ontogenetic quinpirole treatments produce spatial memory deficits and enhance skilled reaching in adult rats.

Authors:  Russell W Brown; Justin T Gass; Richard M Kostrzewa
Journal:  Pharmacol Biochem Behav       Date:  2002-06       Impact factor: 3.533

8.  Developmental exposure to oxytocin facilitates partner preferences in male prairie voles (Microtus ochrogaster).

Authors:  Karen L Bales; C Sue Carter
Journal:  Behav Neurosci       Date:  2003-08       Impact factor: 1.912

9.  Infralimbic D2 receptor influences on anxiety-like behavior and active memory/attention in CD-1 mice.

Authors:  Philip M Wall; Robert J Blanchard; Mu Yang; D Caroline Blanchard
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2003-05       Impact factor: 5.067

Review 10.  Developmental consequences of oxytocin.

Authors:  C Sue Carter
Journal:  Physiol Behav       Date:  2003-08
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  3 in total

Review 1.  Genetics of aggression in voles.

Authors:  Kyle L Gobrogge; Zuoxin W Wang
Journal:  Adv Genet       Date:  2011       Impact factor: 1.944

2.  Neonatal exposure to the D1 agonist SKF38393 inhibits pair bonding in the adult prairie vole.

Authors:  Caroline M Hostetler; Shanna L Harkey; Tarin B Krzywosinski; Brandon J Aragona; Karen L Bales
Journal:  Behav Pharmacol       Date:  2011-10       Impact factor: 2.293

3.  The value of unusual animal models for alcohol research: a commentary on: Anacker, Loftis, and Ryabinin, "alcohol intake in prairie voles is influenced by the drinking level of a peer".

Authors:  Karen L Bales
Journal:  Alcohol Clin Exp Res       Date:  2011-06-08       Impact factor: 3.455
  3 in total

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