Literature DB >> 20151711

A practical chemo-enzymatic synthesis of homochiral bicyclo[2.2.2]octane-2,5-dione.

Yunfei Luo1, Andrew J Carnell.   

Abstract

A practical synthetic route for the preparation of chiral bicyclo[2.2.2]octane-2,5-dione, the precursor of useful chiral diene ligands, was realized via Diels-Alder reaction and resolution of an enol acetate derivative by immobilized lipases.

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Year:  2010        PMID: 20151711     DOI: 10.1021/jo9023705

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Controlling the facial selectivity of asymmetric [4+2] cyclo-additions: a concise synthesis of the cis-decalin core structure of superstolides A and B.

Authors:  Lei Chen; Zhengmao Hua; Gangqin Li; Zhendong Jin
Journal:  Org Lett       Date:  2011-06-14       Impact factor: 6.005

  1 in total

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