Literature DB >> 20151377

The resurgence of acyclic nucleic acids.

Su Zhang1, Christopher Switzer, John C Chaput.   

Abstract

This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly.

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Year:  2010        PMID： 20151377     DOI： 10.1002/cbdv.200900281

Source DB:  PubMed          Journal:  Chem Biodivers        ISSN： 1612-1872            Impact factor:   2.408


  5 in total

1.  227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?

Authors:  H James Cleaves; Markus Meringer; Jay Goodwin
Journal:  Astrobiology       Date:  2015-07       Impact factor: 4.335

2.  Amidate Prodrugs of O-2-Alkylated Pyrimidine Acyclic Nucleosides Display Potent Anti-Herpesvirus Activity.

Authors:  Min Luo; Elisabetta Groaz; Robert Snoeck; Graciela Andrei; Piet Herdewijn
Journal:  ACS Med Chem Lett       Date:  2020-06-24       Impact factor: 4.345

3.  Crystal structure of (S)-1-O-tert-butyl-diphenyl-silylglycerol: eight chiral mol-ecules in a triclinic cell.

Authors:  Bogdan Doboszewski; Alexander Y Nazarenko; Victor N Nemykin; Maria Joselice E Silva
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2018-08-31

4.  Photochemical synthesis of nucleoside analogues from cyclobutanones: bicyclic and isonucleosides.

Authors:  Mileina Jaffer; Abdelaziz Ebead; Edward Lee-Ruff
Journal:  Molecules       Date:  2010-05-26       Impact factor: 4.411

5.  Synthesis of phosphoramidites of isoGNA, an isomer of glycerol nucleic acid.

Authors:  Keunsoo Kim; Venkateshwarlu Punna; Phaneendrasai Karri; Ramanarayanan Krishnamurthy
Journal:  Beilstein J Org Chem       Date:  2014-09-08       Impact factor: 2.883
  5 in total

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