Literature DB >> 20151207

On the (not so) constant proportional trade-off in TTO.

Arthur E Attema1, Werner B F Brouwer.   

Abstract

PURPOSE: The linear and power QALY models require that people in Time Trade-off (TTO) exercises sacrifice the same proportion of lifetime to obtain a health improvement, irrespective of the absolute amount. However, evidence on these constant proportional trade-offs (CPTOs) is mixed, indicating that these versions of the QALY model do not represent preferences. Still, it may be the case that a more general version of the QALY model represents preferences. This version has the property that people want to sacrifice the same proportion of utilities of lifetime for a health improvement, irrespective of the amount of this lifetime.
METHODS: We use a new method to correct TTO scores for utility of life duration and test whether decision makers trade off utility of duration and quality at the same rate irrespective of duration.
RESULTS: We find a robust violation of CPTO for both uncorrected and corrected TTO scores. Remarkably, we find higher values for longer durations, contrary to most previous studies. This represents the only study correcting for utility of life duration to find such a violation.
CONCLUSIONS: It seems that the trade-off of life years is indeed not so constantly proportional and, therefore, that health state valuations depend on durations.

Entities:  

Mesh:

Year:  2010        PMID: 20151207      PMCID: PMC2852526          DOI: 10.1007/s11136-010-9605-9

Source DB:  PubMed          Journal:  Qual Life Res        ISSN: 0962-9343            Impact factor:   4.147


  23 in total

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2.  Axioms for health care resource allocation.

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3.  Can we fix it? Yes we can! But what? A new test of procedural invariance in TTO-measurement.

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Review 4.  The QALY model and individual preferences for health states and health profiles over time: a systematic review of the literature.

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5.  A fallacy of the multiplicative QALY model for low-quality weights in students and patients judging hypothetical health states.

Authors:  P F Stalmeier; G B Chapman; A G de Boer; J J van Lanschot
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6.  Time preference bias in time trade-off.

Authors:  Marjon van der Pol; Larissa Roux
Journal:  Eur J Health Econ       Date:  2005-06

7.  Proportional heuristics in time tradeoff and conjoint measurement.

Authors:  P F Stalmeier; T G Bezembinder; I J Unic
Journal:  Med Decis Making       Date:  1996 Jan-Mar       Impact factor: 2.583

8.  A cost utility analysis of treatment options for gallstone disease: methodological issues and results.

Authors:  J Cook; J Richardson; A Street
Journal:  Health Econ       Date:  1994 May-Jun       Impact factor: 3.046

9.  A new explanation for the difference between time trade-off utilities and standard gamble utilities.

Authors:  Han Bleichrodt
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10.  Assessment of the time-tradeoff values for prophylactic mastectomy of women with a suspected genetic predisposition to breast cancer.

Authors:  I Unic; P F Stalmeier; L C Verhoef; W A van Daal
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  12 in total

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Review 2.  Using QALYs in cancer: a review of the methodological limitations.

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3.  Health Valuation: Demonstrating the Value of Health and Lifespan.

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4.  The way that you do it? An elaborate test of procedural invariance of TTO, using a choice-based design.

Authors:  Arthur E Attema; Werner B F Brouwer
Journal:  Eur J Health Econ       Date:  2011-05-15

5.  Constantly proving the opposite? A test of CPTO using a broad time horizon and correcting for discounting.

Authors:  Arthur E Attema; Werner B F Brouwer
Journal:  Qual Life Res       Date:  2011-04-21       Impact factor: 4.147

6.  EuroQol (EQ-5D) health utility scores for patients with migraine.

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7.  Valuing EQ-5D-Y: the current state of play.

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8.  Health State Utilities for Adverse Events Associated with Chimeric Antigen Receptor T-Cell Therapy in Large B-Cell Lymphoma.

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9.  Time trade-off: one methodology, different methods.

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10.  The time horizon matters: results of an exploratory study varying the timeframe in time trade-off and standard gamble utility elicitation.

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