OBJECTIVE: To describe lipid profile, body shape changes, and cardiovascular risk factors in children and adolescents infected with HIV/AIDS receiving highly active antiretroviral therapy. METHODS: We investigated 43 children and adolescents being treated with this therapy at the outpatient clinic of pediatric infectious diseases of Instituto Fernandes Figueira/Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. Values of total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides were determined. We also performed glucose tolerance test and analyzed body fat distribution, nutritional status, dietary intake, and family history of cardiovascular risk. The statistical analysis was performed using Student's t test. Significance level of p-value was lower than 0.05. RESULTS: We found lipid abnormality in 88.3% and body shape change in 13.9% of the cases. Nutritional status was adequate (81.3%) in most of the study population. Cholesterol intake in children older than 9 years was above the recommended value. CONCLUSION: Prevalence of dyslipidemia and, therefore, risk for cardiovascular diseases were high during the use of highly active antiretroviral therapy.
OBJECTIVE: To describe lipid profile, body shape changes, and cardiovascular risk factors in children and adolescents infected with HIV/AIDS receiving highly active antiretroviral therapy. METHODS: We investigated 43 children and adolescents being treated with this therapy at the outpatient clinic of pediatric infectious diseases of Instituto Fernandes Figueira/Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. Values of total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides were determined. We also performed glucose tolerance test and analyzed body fat distribution, nutritional status, dietary intake, and family history of cardiovascular risk. The statistical analysis was performed using Student's t test. Significance level of p-value was lower than 0.05. RESULTS: We found lipid abnormality in 88.3% and body shape change in 13.9% of the cases. Nutritional status was adequate (81.3%) in most of the study population. Cholesterol intake in children older than 9 years was above the recommended value. CONCLUSION: Prevalence of dyslipidemia and, therefore, risk for cardiovascular diseases were high during the use of highly active antiretroviral therapy.
Authors: Luiz Rodrigo Augustemak de Lima; Edio Luiz Petroski; Yara Maria Franco Moreno; Diego Augusto Santos Silva; Erasmo Benício de Moraes Santos Trindade; Aroldo Prohmann de Carvalho; Isabela de Carlos Back Journal: PLoS One Date: 2018-01-10 Impact factor: 3.240
Authors: Rafaela Catherine da Silva Cunha de Medeiros; Isis Kelly Dos Santos; Anna Luiza Vasconcelos de Oliveira; Carlos Jean Damasceno de Goes; Jason Azevedo de Medeiros; Tatiane Andreza Lima da Silva; Juliany de Souza Araujo; Phelipe Wilde de Alcântara Varela; Ricardo Ney Cobucci; Breno Guilherme de Araújo Tinoco Cabral; Paulo Moreira Silva Dantas Journal: Int J Environ Res Public Health Date: 2021-05-26 Impact factor: 3.390
Authors: Carlos A Rocco; Debora Mecikovsky; Paula Aulicino; Rosa Bologna; Luisa Sen; Andrea Mangano Journal: PLoS One Date: 2012-07-25 Impact factor: 3.240
Authors: Luanda Papi; Ana Carolina G B Menezes; Hélio Rocha; Thalita F Abreu; Ricardo Hugo de Oliveira; Ana Cristina C Frota; Lucia de A Evangelista; Cristina B Hofer Journal: Braz J Infect Dis Date: 2014-04-30 Impact factor: 3.257