Literature DB >> 20150820

Aortic root surgery in Marfan syndrome: Bentall procedure with the composite mechanical valved conduit versus aortic valve reimplantation with Valsalva graft.

Paolo Nardi1, Antonio Pellegrino, Francesco Versaci, Ludmilla Mantione, Patrizio Polisca, Fiore S Iorio, Luigi Chiariello.   

Abstract

OBJECTIVES: The aim of the study is to compare mid-term results of Bentall aortic root replacement with composite mechanical valved conduit and aortic valve reimplantation procedure using the Valsalva graft for the treatment of aortic root aneurysm in patients with Marfan syndrome.
METHODS: We retrospectively compared data of 23 patients (mean age 38 + or - 14 years) who had undergone the Bentall procedure (group B) to those of 24 patients (mean age 36 + or - 12 years) who had undergone aortic valve reimplantation (group R) during a 14-year period. Follow-up (mean duration 65 + or - 44 months) was 100% complete.
RESULTS: There were no operative deaths in either group. In group B, as compared with group R, preoperative aortic insufficiency (3.2 + or - 1.1/4 vs. 1.7 + or - 1.4/4, P < 0.001), ascending aorta diameter (55.8 + or - 4.9 vs. 44.1 + or - 8.7 mm, P = 0.001) were prevailing; cardiopulmonary bypass (107 + or - 51 vs. 145 + or - 32 min, P < 0.05) and aortic cross-clamp (77 + or - 17 vs. 116 + or - 30 min, P = 0.005) times were shorter. Eight-year survival and freedom from cardiac death and reoperation were 91 + or - 6, 96 + or - 4 and 100% in group B and 100, 100 and 91 + or - 6% in group R, respectively (P = NS for all comparisons). At follow-up, echocardiography showed significant improvement of left ventricular ejection fraction (0.60 + or - 0.10 vs. 0.52 + or - 0.09 preoperatively, P = 0.01) and end-systolic diameter (34 + or - 5 vs. 47 + or - 14 mm, P = 0.001) in group B and significant reduction of preoperative aortic insufficiency (0.7 + or - 1.0/4 vs. 1.7 + or - 1.4/4, P = 0.01) and aortic annulus (24 + or - 2.4 vs. 33 + or - 5 mm, P = 0.01) in group R.
CONCLUSION: In Marfan patients, the Bentall procedure is associated with excellent mid-term outcome. The reimplantation technique, adopted for less dilated aortas, provides similarly satisfactory results. The Valsalva graft seems, with time, to allow a stable aortic valve function.

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Year:  2010        PMID: 20150820     DOI: 10.2459/JCM.0b013e3283379998

Source DB:  PubMed          Journal:  J Cardiovasc Med (Hagerstown)        ISSN: 1558-2027            Impact factor:   2.160


  4 in total

1.  Effect of Elective Bentall Procedure on Left Ventricular Systolic Function and Functional Status: Long-Term Follow-Up in 90 patients.

Authors:  Olivera Djokic; Petar Otasevic; Slobodan Micovic; Slobodan Tomic; Predrag Milojevic; Srdjan Boskovic; Bosko Djukanovic
Journal:  Tex Heart Inst J       Date:  2016-04-01

2.  Systematic review and meta-analysis of aortic valve-sparing surgery versus replacement surgery in ascending aortic aneurysms and dissection in patients with Marfan syndrome and other genetic connective tissue disorders.

Authors:  Maria Elena Soto; Eric Ochoa-Hein; Javier E Anaya-Ayala; Micaela Ayala-Picazo; Solange Gabriela Koretzky
Journal:  J Thorac Dis       Date:  2021-08       Impact factor: 3.005

3.  Influence of Bentall Procedure on Left Ventricular Function.

Authors:  Serkan Burç Deşer; Mustafa Kemal Demirag; Semih Murat Yucel; Ufuk Yildirim; Murat Muzaffer Güçlü; Merve Polat; Fersat Kolbakir; Hasan Tahsin Keceligil
Journal:  Braz J Cardiovasc Surg       Date:  2020-02-01

Review 4.  Systematic review and meta-analysis of surgical outcomes in Marfan patients undergoing aortic root surgery by composite-valve graft or valve sparing root replacement.

Authors:  Campbell D Flynn; David H Tian; Ashley Wilson-Smith; Tirone David; George Matalanis; Martin Misfeld; Stefano Mastrobuoni; Gebrine El Khoury; Tristan D Yan
Journal:  Ann Cardiothorac Surg       Date:  2017-11
  4 in total

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