Literature DB >> 20150680

Approximate maximum parsimony and ancestral maximum likelihood.

Noga Alon1, Benny Chor, Fabio Pardi, Anat Rapoport.   

Abstract

We explore the maximum parsimony (MP) and ancestral maximum likelihood (AML) criteria in phylogenetic tree reconstruction. Both problems are NP-hard, so we seek approximate solutions. We formulate the two problems as Steiner tree problems under appropriate distances. The gist of our approach is the succinct characterization of Steiner trees for a small number of leaves for the two distances. This enables the use of known Steiner tree approximation algorithms. The approach leads to a 16/9 approximation ratio for AML and asymptotically to a 1.55 approximation ratio for MP.

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Year:  2010        PMID: 20150680     DOI: 10.1109/TCBB.2008.13

Source DB:  PubMed          Journal:  IEEE/ACM Trans Comput Biol Bioinform        ISSN: 1545-5963            Impact factor:   3.710


  2 in total

1.  Algorithms for reconstruction of chromosomal structures.

Authors:  Vassily Lyubetsky; Roman Gershgorin; Alexander Seliverstov; Konstantin Gorbunov
Journal:  BMC Bioinformatics       Date:  2016-01-19       Impact factor: 3.169

2.  Scelestial: Fast and accurate single-cell lineage tree inference based on a Steiner tree approximation algorithm.

Authors:  Mohammad-Hadi Foroughmand-Araabi; Sama Goliaei; Alice C McHardy
Journal:  PLoS Comput Biol       Date:  2022-08-11       Impact factor: 4.779

  2 in total

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