BACKGROUND AND PURPOSE: Lesion volume measurements in disabling ischemic stroke have excellent reliability, but it is not clear whether this is also true for small lesions. We assessed the reliability of measuring baseline and follow-up lesion volumes in transient ischemic attack and minor stroke. METHODS: Patients who presented with a transient ischemic attack or minor stroke (NIHSS < or = 3) who had brain MRI within 24 hours from symptom onset and at 30-day follow-up and had an acute lesion on baseline MRI were included. Using semiautomated software, 4 stroke fellows independently assessed ischemic lesions twice on acute diffusion-weighted imaging and follow-up fluid-attenuated inversion recovery. RESULTS: Eighty patients were included, with a median baseline NIHSS of 1. Mean baseline diffusion-weighted imaging lesion volume was 3.4+/-7.4 mL (87.5% had <5 mL). There was excellent inter-rater/intrarater reliability, with intraclass correlation coefficients of 0.94/0.96 for acute diffusion-weighted imaging, 0.74/0.92 for follow-up fluid-attenuated inversion recovery, and 0.81/0.93 for growth. CONCLUSIONS: We found excellent concordance between and within raters for acute diffusion-weighted imaging and 30-day follow-up fluid-attenuated inversion recovery lesion volume measurements in patients with transient ischemic attack and minor stroke.
BACKGROUND AND PURPOSE: Lesion volume measurements in disabling ischemic stroke have excellent reliability, but it is not clear whether this is also true for small lesions. We assessed the reliability of measuring baseline and follow-up lesion volumes in transient ischemic attack and minor stroke. METHODS:Patients who presented with a transient ischemic attack or minor stroke (NIHSS < or = 3) who had brain MRI within 24 hours from symptom onset and at 30-day follow-up and had an acute lesion on baseline MRI were included. Using semiautomated software, 4 stroke fellows independently assessed ischemic lesions twice on acute diffusion-weighted imaging and follow-up fluid-attenuated inversion recovery. RESULTS: Eighty patients were included, with a median baseline NIHSS of 1. Mean baseline diffusion-weighted imaging lesion volume was 3.4+/-7.4 mL (87.5% had <5 mL). There was excellent inter-rater/intrarater reliability, with intraclass correlation coefficients of 0.94/0.96 for acute diffusion-weighted imaging, 0.74/0.92 for follow-up fluid-attenuated inversion recovery, and 0.81/0.93 for growth. CONCLUSIONS: We found excellent concordance between and within raters for acute diffusion-weighted imaging and 30-day follow-up fluid-attenuated inversion recovery lesion volume measurements in patients with transient ischemic attack and minor stroke.
Authors: V Nambiar; S I Sohn; M A Almekhlafi; H W Chang; S Mishra; E Qazi; M Eesa; A M Demchuk; M Goyal; M D Hill; B K Menon Journal: AJNR Am J Neuroradiol Date: 2013-12-26 Impact factor: 3.825
Authors: Bino A Varghese; Darryl Hwang; Steven Y Cen; Xiaomeng Lei; Joshua Levy; Bhushan Desai; David J Goodenough; Vinay A Duddalwar Journal: J Appl Clin Med Phys Date: 2021-01-12 Impact factor: 2.102
Authors: Tom van Seeters; Geert Jan Biessels; L Jaap Kappelle; Irene C van der Schaaf; Jan Willem Dankbaar; Alexander D Horsch; Joris M Niesten; Merel J A Luitse; Charles B L M Majoie; Jan Albert Vos; Wouter J Schonewille; Marianne A A van Walderveen; Marieke J H Wermer; Lucien E M Duijm; Koos Keizer; Joseph C J Bot; Marieke C Visser; Aad van der Lugt; Diederik W J Dippel; F Oskar H W Kesselring; Jeannette Hofmeijer; Geert J Lycklama À Nijeholt; Jelis Boiten; Willem Jan van Rooij; Paul L M de Kort; Yvo B W E M Roos; Frederick J A Meijer; C Constantijn Pleiter; Willem P T M Mali; Yolanda van der Graaf; Birgitta K Velthuis Journal: Neuroradiology Date: 2016-01-14 Impact factor: 2.804