Literature DB >> 20150419

A means to an end: ubiquitination of Mpl.

Wei Tong1.   

Abstract

In this issue of Blood, Saur and colleagues report that ubiquitin-mediated degradation of the Mpl receptor constrains Tpo-mediated cell proliferation, highlighting the importance of the E3 ubiquitin ligase c-Cbl in rapid down-regulation of Tpo/Mpl signaling.

Entities:  

Year:  2010        PMID： 20150419      PMCID： PMC2826227          DOI： 10.1182/blood-2009-11-252569

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  10 in total

Review 1.  Myeloproliferative disorders.

Authors:  Ross L Levine; D Gary Gilliland
Journal:  Blood       Date:  2008-09-15       Impact factor: 22.113

2.  beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation.

Authors:  Laure Meyer; Bénédicte Deau; Hana Forejtníková; Dominique Duménil; Florence Margottin-Goguet; Catherine Lacombe; Patrick Mayeux; Frédérique Verdier
Journal:  Blood       Date:  2007-02-27       Impact factor: 22.113

3.  Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia.

Authors:  Michael A Caligiuri; Roger Briesewitz; Jianhua Yu; Lisheng Wang; Min Wei; Kristy J Arnoczky; Trent B Marburger; Jing Wen; Danilo Perrotti; Clara D Bloomfield; Susan P Whitman
Journal:  Blood       Date:  2007-05-02       Impact factor: 22.113

4.  Ubiquitination and degradation of the thrombopoietin receptor c-Mpl.

Authors:  Sebastian J Saur; Veena Sangkhae; Amy E Geddis; Kenneth Kaushansky; Ian S Hitchcock
Journal:  Blood       Date:  2009-10-30       Impact factor: 22.113

5.  Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.

Authors:  Masashi Sanada; Takahiro Suzuki; Lee-Yung Shih; Makoto Otsu; Motohiro Kato; Satoshi Yamazaki; Azusa Tamura; Hiroaki Honda; Mamiko Sakata-Yanagimoto; Keiki Kumano; Hideaki Oda; Tetsuya Yamagata; Junko Takita; Noriko Gotoh; Kumi Nakazaki; Norihiko Kawamata; Masafumi Onodera; Masaharu Nobuyoshi; Yasuhide Hayashi; Hiroshi Harada; Mineo Kurokawa; Shigeru Chiba; Hiraku Mori; Keiya Ozawa; Mitsuhiro Omine; Hisamaru Hirai; Hiromitsu Nakauchi; H Phillip Koeffler; Seishi Ogawa
Journal:  Nature       Date:  2009-07-20       Impact factor: 49.962

6.  Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway.

Authors:  Bentley Varghese; Herve Barriere; Christopher J Carbone; Anamika Banerjee; Gayathri Swaminathan; Alexander Plotnikov; Ping Xu; Junmin Peng; Vincent Goffin; Gergely L Lukacs; Serge Y Fuchs
Journal:  Mol Cell Biol       Date:  2008-06-23       Impact factor: 4.272

7.  YRRL motifs in the cytoplasmic domain of the thrombopoietin receptor regulate receptor internalization and degradation.

Authors:  Ian S Hitchcock; Maximus M Chen; Jennifer R King; Kenneth Kaushansky
Journal:  Blood       Date:  2008-05-16       Impact factor: 22.113

8.  The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells.

Authors:  Chozhavendan Rathinam; Christine B F Thien; Wallace Y Langdon; Hua Gu; Richard A Flavell
Journal:  Genes Dev       Date:  2008-04-15       Impact factor: 11.361

9.  Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia.

Authors:  Rita Sulahian; Ondine Cleaver; Lily Jun-shen Huang
Journal:  Blood       Date:  2009-03-31       Impact factor: 22.113

10.  Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis.

Authors:  K G Suresh Kumar; Hervé Barriere; Christopher J Carbone; Jianghuai Liu; Gayathri Swaminathan; Ping Xu; Ying Li; Darren P Baker; Junmin Peng; Gergely L Lukacs; Serge Y Fuchs
Journal:  J Cell Biol       Date:  2007-12-03       Impact factor: 10.539
  10 in total

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