| Literature DB >> 20149675 |
Lei Liu1, Peng Miao, Yuanyuan Xu, Zhipeng Tian, Zhigang Zou, Genxi Li.
Abstract
The increasing incidence of cancer all over the world demands new, effective and secure materials for treatment. In this paper, we propose Pt/TiO(2) nanocomposite for cancer-cell treatment because noble metal nanoparticles are supposed to enhance the photocatalytic activity of TiO(2) nanoparticles. To evaluate the cancer-cell killing effect of our Pt/TiO(2) nanocomposite, TiO(2) and Au/TiO(2) nanoparticles are also introduced. The prepared Pt/TiO(2) nanocomposite are characterized with transmission electron microscopy (TEM) and UV-vis adsorption spectra. Results of cell treatment indicate that Pt/TiO(2) nanocomposite, as extremely stable metal-semiconductor nanomaterial, can exhibit a very high photodynamic efficiency under a mild ultraviolet radiation. And our Pt/TiO(2) nanocomposite shows to be more effective in cancer-cell treatment than TiO(2) and Au/TiO(2) nanoparticles. As a result, Pt/TiO(2) nanocomposite may be supposed to have a promising application for cancer-cell treatment. Copyright 2010 Elsevier B.V. All rights reserved.Entities:
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Year: 2010 PMID： 20149675 DOI： 10.1016/j.jphotobiol.2010.01.005
Source DB: PubMed Journal: J Photochem Photobiol B ISSN： 1011-1344 Impact factor: 6.252