Literature DB >> 20149361

Failure of the GnRH antagonist ganirelix to block the positive feedback effect of exogenous estrogen in normal women.

Ioannis E Messinis1, Polyxeni Vanakara, Apostolos Zavos, Christina Verikouki, Panagiotis Georgoulias, Konstantinos Dafopoulos.   

Abstract

This study investigated whether the GnRH antagonist ganirelix is able to block the positive-feedback effect of E2 in normal women. Ganirelix was unable to block the positive-feedback effect, suggesting that the clinical efficacy of GnRH antagonists in IVF cycles is determined by the hyperstimulation process. Copyright (c) 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20149361     DOI: 10.1016/j.fertnstert.2009.12.055

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  5 in total

1.  Clinical impact of LH rises prior to and during ganirelix treatment started on day 5 or on day 6 of ovarian stimulation.

Authors:  John L Frattarelli; Torbjörn Hillensjö; Frank J Broekmans; Han Witjes; Jolanda Elbers; Keith Gordon; Bernadette Mannaerts
Journal:  Reprod Biol Endocrinol       Date:  2013-09-12       Impact factor: 5.211

2.  A Patient Friendly Corifollitropin Alfa Protocol without Routine Pituitary Suppression in Normal Responders.

Authors:  Huai-Ling Wang; Hsing-Hua Lai; Tzu-Hsuan Chuang; Yu-Wei Shih; Shih-Chieh Huang; Meng-Ju Lee; Shee-Uan Chen
Journal:  PLoS One       Date:  2016-04-21       Impact factor: 3.240

3.  An extremely patient-friendly and efficient stimulation protocol for assisted reproductive technology in normal and high responders.

Authors:  Chen-Yu Huang; Guan-Yeu Chen; Miawh-Lirng Shieh; Hsin-Yang Li
Journal:  Reprod Biol Endocrinol       Date:  2018-03-05       Impact factor: 5.211

4.  The effect of flexible low-dose GnRH antagonist on pregnancy outcome in the fresh embryo transfer cycle of IVF-ET: a randomized controlled trial.

Authors:  Liping Feng; Ruiqi Fan; Aifang Jiang; Junyi Jiang; Qian Wang; Yujun Sun; Pengyun Qiao; Chune Ren; Tingting Yang
Journal:  Reprod Biol Endocrinol       Date:  2022-03-22       Impact factor: 5.211

5.  Effect of oral Utrogestan in comparison with Cetrotide on preventing luteinizing hormone surge in IVF cycles: A randomized controlled trial.

Authors:  Alieh Ghasemzadeh; Masumeh Dopour Faliz; Laya Farzadi; Nazli Navali; Behzad Bahramzadeh; Arash Fadavi; Parvin Hakimi; Sepideh Tehrani-Ghadim; Sedigheh Abdollahi Fard; Kobra Hamdi
Journal:  Int J Reprod Biomed       Date:  2020-01-27
  5 in total

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