Literature DB >> 2014786

Serum hepatitis B virus DNA in hepatitis B virus seropositive and seronegative patients with normal liver function.

C C Pao1, D S Yao, C Y Lin, S M Kao, K C Tsao, C F Sun, Y F Liaw.   

Abstract

The presence of hepatitis type B virus (HBV) DNA in serum specimens from 926 apparently healthy people with normal liver functions was determined by polymerase chain reaction; 41.2% of people with positive results for HBV surface antigen (HBsAg) (94 of 228) and 95.2% of people with positive results for HBV e antigen (HBeAg) (60 of 63) were found to have positive results for serum HBV DNA. On the other hand, serum HBV DNA was found in 11.0% (77 of 698) of HBsAg-negative people and in 13% (69 of 530) of those who had positive results for serum antibodies directed against HBsAg. The results seem to suggest that HBV DNA can be found in a significant portion of apparently healthy people with normal liver function who are either seronegative for HBsAg or seropositive for antibodies directed against HBsAg.

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Year:  1991        PMID: 2014786     DOI: 10.1093/ajcp/95.4.591

Source DB:  PubMed          Journal:  Am J Clin Pathol        ISSN: 0002-9173            Impact factor:   2.493


  6 in total

Review 1.  Immunodiagnosis of viral hepatitides A to E and non-A to -E.

Authors:  G Yang; G N Vyas
Journal:  Clin Diagn Lab Immunol       Date:  1996-05

2.  Hepatitis B and C virus infections in Turkish children with cancer.

Authors:  E Kocabaş; N Aksaray; E Alhan; A Tanyeli; F Köksal; F Yarkin
Journal:  Eur J Epidemiol       Date:  1997-12       Impact factor: 8.082

3.  Frequent chronic hepatitis B virus infection in HIV-infected patients positive for antibody to hepatitis B core antigen only. Swiss HIV Cohort Study.

Authors:  M Hofer; H I Joller-Jemelka; P J Grob; R Lüthy; M Opravil
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1998-01       Impact factor: 3.267

4.  Evaluation of SHARP signal system for enzymatic detection of amplified hepatitis B virus DNA.

Authors:  E Valentine-Thon
Journal:  J Clin Microbiol       Date:  1995-02       Impact factor: 5.948

5.  Possible non-sexual transmission of genital human papillomavirus infections in young women.

Authors:  C C Pao; P L Tsai; Y L Chang; T T Hsieh; J Y Jin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993-03       Impact factor: 3.267

6.  Serum levels of interferon-alpha and -gamma in acute and chronic hepatitis B virus infection.

Authors:  C M Chu; I S Sheen; C T Yeh; S Y Hsieh; S L Tsai; Y F Liaw
Journal:  Dig Dis Sci       Date:  1995-10       Impact factor: 3.199

  6 in total

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