Literature DB >> 20146479

Small molecule JNK (c-Jun N-terminal kinase) inhibitors.

M Arshad Siddiqui1, Panduranga A Reddy.   

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Year:  2010        PMID: 20146479     DOI: 10.1021/jm9003279

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  16 in total

1.  Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.

Authors:  John L Stebbins; Surya K De; Petra Pavlickova; Vida Chen; Thomas Machleidt; Li-Hsing Chen; Christian Kuntzen; Shinichi Kitada; Michael Karin; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2011-08-23       Impact factor: 7.446

Review 2.  JNK signalling in cancer: in need of new, smarter therapeutic targets.

Authors:  Concetta Bubici; Salvatore Papa
Journal:  Br J Pharmacol       Date:  2014-01       Impact factor: 8.739

Review 3.  JNK signaling as a target for anticancer therapy.

Authors:  Kamal S Abdelrahman; Heba A Hassan; Salah A Abdel-Aziz; Adel A Marzouk; Atsushi Narumi; Hiroyuki Konno; Mohamed Abdel-Aziz
Journal:  Pharmacol Rep       Date:  2021-03-12       Impact factor: 3.024

4.  Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.

Authors:  Yuanjun He; Derek Duckett; Weimin Chen; Yuan Yuan Ling; Michael D Cameron; Li Lin; Claudia H Ruiz; Philip V Lograsso; Theodore M Kamenecka; Marcel Koenig
Journal:  Bioorg Med Chem Lett       Date:  2013-12-04       Impact factor: 2.823

5.  Suzuki-Miyaura cross-coupling of unprotected, nitrogen-rich heterocycles: substrate scope and mechanistic investigation.

Authors:  M Alexander Düfert; Kelvin L Billingsley; Stephen L Buchwald
Journal:  J Am Chem Soc       Date:  2013-08-16       Impact factor: 15.419

6.  Radiolabeled Aminopyrazoles as Novel Isoform Selective Probes for pJNK3 Quantification.

Authors:  Brian C Bales; Victoria Cotero; Dan E Meyer; Jeannette C Roberts; Monica Rodriguez-Silva; Tiberiu M Siclovan; Jeremy W Chambers; Michael J Rishel
Journal:  ACS Med Chem Lett       Date:  2022-09-28       Impact factor: 4.632

7.  From in Silico Discovery to intra-Cellular Activity: Targeting JNK-Protein Interactions with Small Molecules.

Authors:  Tamer S Kaoud; Chunli Yan; Shreya Mitra; Chun-Chia Tseng; Jiney Jose; Juliana M Taliaferro; Maidina Tuohetahuntila; Ashwini Devkota; Rachel Sammons; Jihyun Park; Heekwang Park; Yue Shi; Jiyong Hong; Pengyu Ren; Kevin N Dalby
Journal:  ACS Med Chem Lett       Date:  2012-08-06       Impact factor: 4.345

8.  Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives.

Authors:  Ke Zheng; Sarah Iqbal; Pamela Hernandez; HaJeung Park; Philip V LoGrasso; Yangbo Feng
Journal:  J Med Chem       Date:  2014-11-21       Impact factor: 7.446

Review 9.  JNK at the crossroad of obesity, insulin resistance, and cell stress response.

Authors:  Giovanni Solinas; Barbara Becattini
Journal:  Mol Metab       Date:  2016-12-08       Impact factor: 7.422

Review 10.  c-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer's Disease.

Authors:  Ramon Yarza; Silvia Vela; Maite Solas; Maria J Ramirez
Journal:  Front Pharmacol       Date:  2016-01-12       Impact factor: 5.810

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