| Literature DB >> 20145301 |
R-L Han1, X-Y Lan, L-Z Zhang, G Ren, Y-J Jing, M-J Li, B Zhang, M Zhao, Y-K Guo, X-T Kang, H Chen.
Abstract
Visfatin is a peptide that is predominantly expressed in visceral adipose tissue and is hypothesized to be related to obesity and insulin resistance. In this study, a novel silent single-nucleotide polymorphism (SNP) was found in exon 7 of the chicken visfatin gene (also known as PBEF1) by single-stranded conformation polymorphism (SSCP) and DNA sequencing. In total, 836 chickens forming an F2 resource population of Gushi chicken crossed with Anka broiler were genotyped by XbaI forced RFLP, and the associations of this polymorphism with chicken growth, carcass characteristics, and meat quality were analyzed. Significant associations were found between the polymorphism and 4-week body weight (BW4), 6-week body weight (BW6), 4-week body slanting length (BSL4), fat bandwidth (FBW), breast muscle water loss rate (BWLR) and breast muscle fiber density (BFD) (P < 0.05), as well as 4-week breastbone length (BBL4) (P < 0.01). These observations suggested that the polymorphism in exon7 of the visfatin gene had significant effects on the early growth traits of chicken.Entities:
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Year: 2010 PMID： 20145301 DOI： 10.1007/BF03195711
Source DB: PubMed Journal: J Appl Genet ISSN： 1234-1983 Impact factor: 3.240