Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 BRAF inhibitors: research accelerates in wake of positive findings.

× No keyword cloud information.

8 in total

Review 1. Targeting the MAPK pathway in melanoma: why some approaches succeed and other fail.

Authors: Gajanan S Inamdar; SubbaRao V Madhunapantula; Gavin P Robertson
Journal: Biochem Pharmacol Date: 2010-05-09 Impact factor: 5.858

2. Copy number gains in 11q13 and 8q24 [corrected] are highly linked to prognosis in cutaneous malignant melanoma.

Authors: Pedram Gerami; Susan S Jewell; Pedram Pouryazdanparast; Jeffery D Wayne; Zahra Haghighat; Klaus J Busam; Alfred Rademaker; Larry Morrison
Journal: J Mol Diagn Date: 2011-05 Impact factor: 5.568

3. Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032.

Authors: Maria J Sambade; Eldon C Peters; Nancy E Thomas; William K Kaufmann; Randall J Kimple; Janiel M Shields
Journal: Radiother Oncol Date: 2011-02-04 Impact factor: 6.280

4. The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit.

Authors: Kimberly Lin; Stavroula Baritaki; Loredana Militello; Graziella Malaponte; Ylenia Bevelacqua; Benjamin Bonavida
Journal: Genes Cancer Date: 2010-05

BRAF inhibitors: research accelerates in wake of positive findings.

Review 1. Targeting the MAPK pathway in melanoma: why some approaches succeed and other fail.

2. Copy number gains in 11q13 and 8q24 [corrected] are highly linked to prognosis in cutaneous malignant melanoma.

3. Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032.

4. The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit.

Review 5. Current and future trials of targeted therapies in cutaneous melanoma.

6. Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma.

Review 7. Ras and Raf pathways in epidermis development and carcinogenesis.

Review 8. Ibrutinib and novel BTK inhibitors in clinical development.