| Literature DB >> 20144894 |
Robert E Clark1, Larry R Squire.
Abstract
The medial temporal lobe includes a system of anatomically connected structures that are essential for declarative memory (conscious memory for facts and events). A prominent form of declarative memory is recognition memory (the ability to identify a recently encountered item as familiar). Recognition memory has been frequently assessed in humans and in the experimental animal. This article traces the successful development of an animal model of human medial temporal lobe amnesia, which eventually identified the structures in the medial temporal lobe important for memory. Attention is given to two prominent behavioral paradigms (delayed nonmatching to sample and tests of spontaneous novelty preference).Entities:
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Year: 2010 PMID： 20144894 PMCID： PMC2975590 DOI： 10.1016/j.neuropsychologia.2010.02.004
Source DB: PubMed Journal: Neuropsychologia ISSN： 0028-3932 Impact factor: 3.139