| Literature DB >> 20144769 |
Lorenzo Galluzzi1, Oliver Kepp, Laurence Zitvogel, Guido Kroemer.
Abstract
Crohn's disease is a chronic inflammatory bowel disorder that has been associated with polymorphisms in the genes encoding the pattern-recognition receptor NOD2 and the autophagic regulator ATG16L1. A new study demonstrates that NOD2 recruits ATG16L1 at bacterial entry sites, thereby bridging innate immunity and autophagy.Entities:
Mesh：
Substances：
Year: 2010 PMID： 20144769 DOI： 10.1016/j.cub.2009.12.016
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834