Literature DB >> 20143790

Synthesis and biological evaluation of heteroanalogues of kotalanol and de-O-sulfonated kotalanol.

Sankar Mohan1, Kumarasamy Jayakanthan, Ravindranath Nasi, Douglas A Kuntz, David R Rose, B Mario Pinto.   

Abstract

The synthesis of nitrogen and selenium analogues of kotalanol and de-O-sulfonated kotalanol, naturally occurring sulfonium-ion glucosidase inhibitors isolated from Salacia reticulata, and their evaluation as glucosidase inhibitors against the N-terminal catalytic domain of human maltase glucoamylase (ntMGAM) are described.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20143790     DOI: 10.1021/ol100080m

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  Quantitative analysis of neosalacinol and neokotalanol, another two potent α-glucosidase inhibitors from Salacia species, by LC-MS with ion pair chromatography.

Authors:  Osamu Muraoka; Toshio Morikawa; Sohachiro Miyake; Junji Akaki; Kiyofumi Ninomiya; Yutana Pongpiriyadacha; Masayuki Yoshikawa
Journal:  J Nat Med       Date:  2010-10-28       Impact factor: 2.343

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.