BACKGROUND:Deep inferior epigastric perforator flap surgery usually results in postoperative pain from the donor site requiring opioids. METHOD: We examined the effect of bupivacaine 2.5 mg/mL, 20 mL given every third hour for 72 hours postoperatively through 2 thin catheters placed on the donor site in a double-blind placebo-controlled study consisting of 2 x 20 patients. RESULTS: The bupivacaine group had significantly reduced pain at rest and during coughing. The placebo group needed 2 to 3 times more opioids in the 72-hour observation period. No difference was seen in the frequency of nausea or the consumption of antiemetic drugs. CONCLUSION: We conclude that intermittent delivery of bupivacaine at the abdominal donor site significantly reduces the postoperative pain and need for narcotic rescue medication.
RCT Entities:
BACKGROUND: Deep inferior epigastric perforator flap surgery usually results in postoperative pain from the donor site requiring opioids. METHOD: We examined the effect of bupivacaine 2.5 mg/mL, 20 mL given every third hour for 72 hours postoperatively through 2 thin catheters placed on the donor site in a double-blind placebo-controlled study consisting of 2 x 20 patients. RESULTS: The bupivacaine group had significantly reduced pain at rest and during coughing. The placebo group needed 2 to 3 times more opioids in the 72-hour observation period. No difference was seen in the frequency of nausea or the consumption of antiemetic drugs. CONCLUSION: We conclude that intermittent delivery of bupivacaine at the abdominal donor site significantly reduces the postoperative pain and need for narcotic rescue medication.
Authors: Toni Zhong; Marie Ojha; Shaghayegh Bagher; Kate Butler; Anne C O'Neill; Stuart A McCluskey; Hance Clarke; Stefan O P Hofer; Coimbatore Srinivas Journal: Trials Date: 2013-12-10 Impact factor: 2.279
Authors: Ariel Clare Johnson; Salih Colakoglu; Angela Reddy; Clara Marie Kerwin; Roland A Flores; Matthew L Iorio; David W Mathes Journal: Anesth Pain Med Date: 2020-10-23