Literature DB >> 20142032

On-bead library screening made easier.

Dehua Pei1.   

Abstract

In this issue of Chemistry & Biology, Astle et al. report the rapid identification of the most active hits from a large one-bead-one-compound peptoid library by magnetic sorting and without the need for labor-intensive resynthesis of the hits. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2010        PMID： 20142032      PMCID： PMC2829754          DOI： 10.1016/j.chembiol.2010.01.003

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  9 in total

1.  A novel and rapid encoding method based on mass spectrometry for "one-bead-one-compound" small molecule combinatorial libraries.

Authors:  Aimin Song; Jinhua Zhang; Carlito B Lebrilla; Kit S Lam
Journal:  J Am Chem Soc       Date:  2003-05-21       Impact factor: 15.419

2.  Applications of topologically segregated bilayer beads in 'one-bead one-compound' combinatorial libraries.

Authors:  X Wang; L Peng; R Liu; B Xu; K S Lam
Journal:  J Pept Res       Date:  2005-01

3.  Cleavable hydrophilic linker for one-bead-one-compound sequencing of oligomer libraries by tandem mass spectrometry.

Authors:  Margot G Paulick; Kathryn M Hart; Kristin M Brinner; Meiliana Tjandra; Deborah H Charych; Ronald N Zuckermann
Journal:  J Comb Chem       Date:  2006 May-Jun

4.  A new type of synthetic peptide library for identifying ligand-binding activity.

Authors:  K S Lam; S E Salmon; E M Hersh; V J Hruby; W M Kazmierski; R J Knapp
Journal:  Nature       Date:  1991-11-07       Impact factor: 49.962

5.  Single bead labeling method for combining confocal fluorescence on-bead screening and solution validation of tagged one-bead one-compound libraries.

Authors:  Martin Hintersteiner; Thierry Kimmerlin; Frank Kalthoff; Markus Stoeckli; Geraldine Garavel; Jan-Marcus Seifert; Nicole-Claudia Meisner; Volker Uhl; Christof Buehler; Thomas Weidemann; Manfred Auer
Journal:  Chem Biol       Date:  2009-07-31

6.  Complex synthetic chemical libraries indexed with molecular tags.

Authors:  M H Ohlmeyer; R N Swanson; L W Dillard; J C Reader; G Asouline; R Kobayashi; M Wigler; W C Still
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-01       Impact factor: 11.205

7.  Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries.

Authors:  John M Astle; Levi S Simpson; Yong Huang; M Muralidhar Reddy; Rosemary Wilson; Steven Connell; Johnnie Wilson; Thomas Kodadek
Journal:  Chem Biol       Date:  2010-01-29

8.  On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.

Authors:  Xianwen Chen; Pauline H Tan; Yanyan Zhang; Dehua Pei
Journal:  J Comb Chem       Date:  2009 Jul-Aug

9.  High-throughput sequencing of peptoids and peptide-peptoid hybrids by partial edman degradation and mass spectrometry.

Authors:  Amit Thakkar; Allison S Cohen; Michael D Connolly; Ronald N Zuckermann; Dehua Pei
Journal:  J Comb Chem       Date:  2009-03-09
  9 in total
  5 in total

1.  Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries.

Authors:  Choi-Fong Cho; Kyungheon Lee; Maria-Carmela Speranza; Fernanda C Bononi; Mariano S Viapiano; Leonard G Luyt; Ralph Weissleder; E Antonio Chiocca; Hakho Lee; Sean E Lawler
Journal:  ACS Comb Sci       Date:  2016-05-23       Impact factor: 3.784

Review 2.  Methods for the discovery of small molecules to monitor and perturb the activity of the human proteasome.

Authors:  Marianne E Maresh; Andres F Salazar-Chaparro; Darci J Trader
Journal:  Future Med Chem       Date:  2020-12-04       Impact factor: 3.808

Review 3.  Solid-phase synthesis of N-substituted glycine oligomers (alpha-peptoids) and derivatives.

Authors:  Adrian S Culf; Rodney J Ouellette
Journal:  Molecules       Date:  2010-08-04       Impact factor: 4.411

4.  Mega-High-Throughput Screening Platform for the Discovery of Biologically Relevant Sequence-Defined Non-Natural Polymers.

Authors:  Michal Avital-Shmilovici; Xiaohe Liu; Thomas Shaler; Andrew Lowenthal; Pauline Bourbon; Janey Snider; Arlyn Tambo-Ong; Claire Repellin; Kenya Yniguez; Lidia Sambucetti; Peter B Madrid; Nathan Collins
Journal:  ACS Cent Sci       Date:  2022-01-11       Impact factor: 14.553

5.  Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding.

Authors:  Martin Hintersteiner; Jörg Kallen; Mario Schmied; Christine Graf; Thomas Jung; Gemma Mudd; Steven Shave; Hubert Gstach; Manfred Auer
Journal:  Angew Chem Int Ed Engl       Date:  2014-04-01       Impact factor: 15.336
  5 in total

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