BACKGROUND: Bupropion's efficacy for smoking cessation in pregnant women is unknown. OBJECTIVES: To determine if substance-dependent women prescribed bupropion smoked fewer cigarettes/day than those prescribed citalopram/escitalopram or no antidepressant medication. METHODS: Comparison of smoking in bupropion (n = 11), citalopram/escitalopram (n = 17), and no antidepressant (n = 28) groups. RESULTS AND CONCLUSIONS: Trend for greater decrease in smoking for the bupropion vs. citalopram/escitalopram group [-6.4 vs. -.4 cigarettes/day (p = .276)], although the bupropion decrease was similar to that seen in the no antidepressant group [-5.3 cigarettes/day]. SCIENTIFIC SIGNIFICANCE: Data support continued study of bupropion in depressed pregnant substance-dependent smokers.
BACKGROUND:Bupropion's efficacy for smoking cessation in pregnant women is unknown. OBJECTIVES: To determine if substance-dependent women prescribed bupropion smoked fewer cigarettes/day than those prescribed citalopram/escitalopram or no antidepressant medication. METHODS: Comparison of smoking in bupropion (n = 11), citalopram/escitalopram (n = 17), and no antidepressant (n = 28) groups. RESULTS AND CONCLUSIONS: Trend for greater decrease in smoking for the bupropion vs. citalopram/escitalopram group [-6.4 vs. -.4 cigarettes/day (p = .276)], although the bupropion decrease was similar to that seen in the no antidepressant group [-5.3 cigarettes/day]. SCIENTIFIC SIGNIFICANCE: Data support continued study of bupropion in depressed pregnant substance-dependent smokers.
Authors: Ronit Calderon-Margalit; Chunfang Qiu; Asher Ornoy; David S Siscovick; Michelle A Williams Journal: Am J Obstet Gynecol Date: 2009-08-18 Impact factor: 8.661
Authors: Margaret S Chisolm; Heather Fitzsimons; Jeannie-Marie S Leoutsakos; Shauna P Acquavita; Sarah H Heil; Molly Wilson-Murphy; Michelle Tuten; Karol Kaltenbach; Peter R Martin; Bernadette Winklbaur; Lauren M Jansson; Hendrée E Jones Journal: Nicotine Tob Res Date: 2013-01-03 Impact factor: 4.244