OBJECTIVE: The purpose of this work was to analyse drugs prescribed in the first month of life among a group of newborns admitted to the Neonatal Intensive Care Unit and Neonatal Pathology of Cagliari University Hospital. METHOD: This pilot study was prospectively conducted during a 1-month period and involved all newborns admitted to our hospital that received a pharmacotherapy. After obtaining written parental consent, data collected from each newborn included date of birth, sex, gestational age and weight. Also, diagnosis and information about each drug administered during the first month of life: dose, frequency, route of administration, and indication for use was collected. RESULTS: Among the 79 newborn infants admitted to our hospital during the study period, 38 received a pharmacotherapy and were enrolled in our study. A total of 88 treatments were given: 41 (47%) followed the terms of the product license, 47 (53%) were used in an unlicensed or off-label manner. CONCLUSION: Our results confirm this trend of drug use in the neonatological field and suggest the need to update information contained in the data sheets of medicines.
OBJECTIVE: The purpose of this work was to analyse drugs prescribed in the first month of life among a group of newborns admitted to the Neonatal Intensive Care Unit and Neonatal Pathology of Cagliari University Hospital. METHOD: This pilot study was prospectively conducted during a 1-month period and involved all newborns admitted to our hospital that received a pharmacotherapy. After obtaining written parental consent, data collected from each newborn included date of birth, sex, gestational age and weight. Also, diagnosis and information about each drug administered during the first month of life: dose, frequency, route of administration, and indication for use was collected. RESULTS: Among the 79 newborn infants admitted to our hospital during the study period, 38 received a pharmacotherapy and were enrolled in our study. A total of 88 treatments were given: 41 (47%) followed the terms of the product license, 47 (53%) were used in an unlicensed or off-label manner. CONCLUSION: Our results confirm this trend of drug use in the neonatological field and suggest the need to update information contained in the data sheets of medicines.
Authors: Ermindo R Di Paolo; Hans Stoetter; Jacques Cotting; Peter Frey; Mario Gehri; Maja Beck-Popovic; Jean-François Tolsa; Sergio Fanconi; André Pannatier Journal: Swiss Med Wkly Date: 2006-04-01 Impact factor: 2.193
Authors: A Ceci; M Felisi; P Baiardi; F Bonifazi; M Catapano; C Giaquinto; A Nicolosi; M Sturkenboom; A Neubert; I Wong Journal: Eur J Clin Pharmacol Date: 2006-10-05 Impact factor: 2.953
Authors: Anna Girardi; Emanuel Raschi; Silvia Galletti; Elisabetta Poluzzi; Giacomo Faldella; Karel Allegaert; Fabrizio De Ponti Journal: Drug Saf Date: 2015-06 Impact factor: 5.606