| Literature DB >> 20140157 |
L Mannarini1, V Kratochvil, L Calabrese, L Gomes Silva, P Morbini, J Betka, M Benazzo.
Abstract
The evidence that human papillomavirus infection is related to head and neck squamous cell carcinoma is supported by molecular and epidemiological data. The definition of a distinct subset of head and neck squamous cell carcinoma, independent of the traditional risk factors and with different clinical presentation and outcome, has led to increasing interest in human papillomavirus infection. This review summarizes current knowledge regarding human papillomavirus biology, oncogenic mechanisms, risk factors for transmission, clinical significance and prophylactic strategies.Entities:
Keywords: Head and neck; Human papillomavirus; Oral cavity; Oropharynx; Squamous cell carcinoma
Mesh:
Year: 2009 PMID: 20140157 PMCID: PMC2815356
Source DB: PubMed Journal: Acta Otorhinolaryngol Ital ISSN: 0392-100X Impact factor: 2.124