Literature DB >> 20139824

Epstein-Barr virus mimicking lymphoma on FDG-PET/CT.

Damita L Thomas1, Sergei Syrbu, Michael M Graham.   

Abstract

We report the case of a 17-year-old girl who presented with a several month history of fevers and abdominal pain. After cytomegalovirus (CMV) and Epstein-Barr virus (EBV) titers returned normal, FDG-PET/CT was obtained due to concern for lymphoma. FDG-PET/CT revealed a pattern of hypermetabolic activity in the adenoids, bilateral cervical lymph nodes, abdominal lymph nodes, and spleen, highly concerning for lymphoma. However, subsequent biopsy of a cervical lymph node revealed lymphadenitis consistent with EBV. This case highlights infection as the most well-known false-positive cause on FDG-PET, and how biopsy is essential to definitively distinguish malignancy from infection.

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Year:  2009        PMID: 20139824     DOI: 10.1097/RLU.0b013e3181bed135

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  9 in total

1.  Chronic HIV-1 infection mimicking splenic malignant lymphoma on F-18 FDG-PET/CT.

Authors:  Florent Valour; Agathe Sénéchal; Christian Chidiac; Tristan Ferry
Journal:  BMJ Case Rep       Date:  2012-01-18

Review 2.  Postoperative reactive lymphadenitis: A potential cause of false-positive FDG PET/CT.

Authors:  Yiyan Liu
Journal:  World J Radiol       Date:  2014-12-28

3.  18F-FDG PET/CT for identifying the potential causes and extent of secondary hemophagocytic lymphohistiocytosis.

Authors:  Leilei Yuan; Ying Kan; Jacqui K Meeks; Daqing Ma; Jigang Yang
Journal:  Diagn Interv Radiol       Date:  2016 Sep-Oct       Impact factor: 2.630

4.  Systemic Immune Response to Vaccination on FDG-PET/CT.

Authors:  Mark Mingos; Stephanie Howard; Nicholas Giacalone; David Kozono; Heather Jacene
Journal:  Nucl Med Mol Imaging       Date:  2015-12-09

5.  A rare B-cell type chronic active Epstein-Barr virus infection patient mimicking lymphoma on 18F-FDG PET/CT and literature review.

Authors:  Hao Jiao; Yongbai Zhang; Zhao Chen; Xueqi Chen; Yongkang Qiu; Wenpeng Huang; Lin Nong; Lei Kang
Journal:  Am J Nucl Med Mol Imaging       Date:  2022-08-20

6.  Primary Epstein-Barr virus infection diffusing F18-fluorodeoxyglucose-positron emission tomography/computed tomography response monitoring of Hodgkin's disease: a case report.

Authors:  Hans Balink; Mels Hoogendoorn
Journal:  J Med Case Rep       Date:  2014-06-20

7.  Development and Validation of a Nomogram Based on 18F-FDG PET/CT Radiomics to Predict the Overall Survival in Adult Hemophagocytic Lymphohistiocytosis.

Authors:  Xu Yang; Jun Liu; Xia Lu; Ying Kan; Wei Wang; Shuxin Zhang; Lei Liu; Hui Zhang; Jixia Li; Jigang Yang
Journal:  Front Med (Lausanne)       Date:  2021-12-22

8.  The Role of Pre-therapeutic 18F-FDG PET/CT in Pediatric Hemophagocytic Lymphohistiocytosis With Epstein-Barr Virus Infection.

Authors:  Xia Lu; Ang Wei; Xu Yang; Jun Liu; Siqi Li; Ying Kan; Wei Wang; Tianyou Wang; Rui Zhang; Jigang Yang
Journal:  Front Med (Lausanne)       Date:  2022-01-21

9.  (18)F-FDG PET/CT Findings in Acute Epstein-Barr Virus Infection Mimicking Malignant Lymphoma.

Authors:  Mathilde Ørbæk; Jesper Graff; Elena Markova; Gitte Kronborg; Anne-Mette Lebech
Journal:  Diagnostics (Basel)       Date:  2016-05-12
  9 in total

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