Literature DB >> 20138747

Longitudinal trajectories of ketamine use among young injection drug users.

Stephen E Lankenau1, Jennifer Jackson Bloom, Charles Shin.   

Abstract

BACKGROUND: Ketamine is a dissociative anaesthetic that became increasingly popular in the club and rave scene in the 1980s and 1990s. Reports surfaced in the late 1990s indicating that ketamine was being injected in several U.S. cities by young injection drug users (IDUs). Since all studies on ketamine injection were cross-sectional, a longitudinal study was undertaken in 2005 to determine: characteristics of young IDUs who continue to inject ketamine; frequency of ketamine injection over an extended time period; risks associated with ongoing ketamine injection; and environmental factors that impact patterns of ketamine use.
METHODS: Young IDUs aged 16-29 with a history of injecting ketamine (n=101) were recruited from public locations in Los Angeles and followed during a 2-year longitudinal study. A semi-structured instrument captured quantitative and qualitative data on patterns of ketamine injection and other drug use. A statistical model sorted IDUs who completed three or more interviews (n=66) into three groups based upon patterns of ketamine injection at baseline and follow-up. Qualitative analysis focused on detailed case studies within each group.
RESULTS: IDUs recruited at baseline were typically in their early 20s, male, heterosexual, white, and homeless. Longitudinal injection trajectories included: "Moderates," who injected ketamine several times per year (n=5); "Occasionals," who injected ketamine approximately once per year (n=21); and "Abstainers," who did not inject any ketamine during follow-up (n=40). Findings suggest that ketamine is infrequently injected compared to other drugs such as heroin, cocaine, and methamphetamine. Most IDUs who begin injecting ketamine will stop or curb use due to: negative or ambivalent experiences associated with ketamine; an inability to find the drug due to declining supply; or maturing out of injecting drugs more generally.
CONCLUSION: Reducing ketamine injection among young IDUs may best be accomplished by targeting particular groups of IDUs identified in this study, such as homeless youth and homeless travellers. Copyright (c) 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20138747      PMCID: PMC2890290          DOI: 10.1016/j.drugpo.2010.01.007

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  16 in total

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3.  Hitting a moving target: the use of ethnographic methods in the development of sampling strategies for the evaluation of AIDS outreach programs for homeless youth in New York City.

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4.  Patterns of polydrug use among ketamine injectors in New York City.

Authors:  Stephen E Lankenau; Michael C Clatts
Journal:  Subst Use Misuse       Date:  2005       Impact factor: 2.164

5.  THE FIRST INJECTION EVENT: DIFFERENCES AMONG HEROIN, METHAMPHETAMINE, COCAINE, AND KETAMINE INITIATES.

Authors:  Stephen E Lankenau; Karla D Wagner; Jennifer Jackson Bloom; Bill Sanders; Dodi Hathazi; Charles Shin
Journal:  J Drug Issues       Date:  2010

6.  Recruiting and retaining mobile young injection drug users in a longitudinal study.

Authors:  Stephen E Lankenau; Bill Sanders; Dodi Hathazi; Jennifer Jackson Bloom
Journal:  Subst Use Misuse       Date:  2010-04       Impact factor: 2.164

7.  Traveling young injection drug users at high risk for acquisition and transmission of viral infections.

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8.  Patterns of use and harms associated with non-medical ketamine use.

Authors:  Paul Dillon; Jan Copeland; Karl Jansen
Journal:  Drug Alcohol Depend       Date:  2003-01-24       Impact factor: 4.492

9.  Towards an Explanation of Subjective Ketamine Experiences among Young Injection Drug Users.

Authors:  Stephen E Lankenau; Bill Sanders; Jennifer Jackson Bloom; Dodi Hathazi
Journal:  Addict Res Theory       Date:  2008

10.  Ketamine Injection among High Risk Youth: Preliminary Findings from New York City.

Authors:  Stephen E Lankenau; Michael C Clatts
Journal:  J Drug Issues       Date:  2002-06
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  5 in total

1.  Initiation into prescription drug misuse: differences between lesbian, gay, bisexual, transgender (LGBT) and heterosexual high-risk young adults in Los Angeles and New York.

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Authors:  Stephen E Lankenau; Avat Kioumarsi; Megan Reed; Miles McNeeley; Ellen Iverson; Carolyn F Wong
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3.  Pharmacological and non-pharmacological factors that regulate the acquisition of ketamine self-administration in rats.

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Journal:  Psychopharmacology (Berl)       Date:  2015-09-21       Impact factor: 4.530

4.  Health conditions and motivations for marijuana use among young adult medical marijuana patients and non-patient marijuana users.

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Review 5.  Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans.

Authors:  Ke Xu; Robert H Lipsky
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