Literature DB >> 2013815

Parametric images of myocardial metabolic rate of glucose generated from dynamic cardiac PET and 2-[18F]fluoro-2-deoxy-d-glucose studies.

Y Choi1, R A Hawkins, S C Huang, S S Gambhir, R C Brunken, M E Phelps, H R Schelbert.   

Abstract

We describe a method for generating parametric images of the myocardial metabolic rate of glucose (MMRGlc) with positron emission tomography (PET). The method employs serially acquired images of 2-[18F]fluoro-2-deoxy-D-glucose (FDG) uptake and a Patlak graphical analysis of the image data. The arterial input function is derived from images of the left ventricular blood pool calibrated with 18F-plasma measurements. The approach is computationally fast enough to be used in a clinical environment. The MMRGlc parametric images improve myocardial contrast relative to non-parametric images, especially in studies with poor myocardial uptake of FDG. In addition, MMRGlc parametric images consolidate the large amount of data in a dynamic PET study into a clinically usable image set.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 2013815

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  33 in total

1.  PET myocardial perfusion and glucose metabolism imaging: Part 2-Guidelines for interpretation and reporting.

Authors:  Heinrich R Schelbert; Robert Beanlands; Frank Bengel; Juhani Knuuti; Marcelo Dicarli; Josef Machac; Randolph Patterson
Journal:  J Nucl Cardiol       Date:  2003 Sep-Oct       Impact factor: 5.952

Review 2.  PET/CT: a new imaging technology in nuclear medicine.

Authors:  Heiko Schöder; Yusuf E Erdi; Steven M Larson; Henry W D Yeung
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-09-05       Impact factor: 9.236

Review 3.  Dynamic single photon emission computed tomography--basic principles and cardiac applications.

Authors:  Grant T Gullberg; Bryan W Reutter; Arkadiusz Sitek; Jonathan S Maltz; Thomas F Budinger
Journal:  Phys Med Biol       Date:  2010-09-22       Impact factor: 3.609

4.  EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology.

Authors:  B Hesse; K Tägil; A Cuocolo; C Anagnostopoulos; M Bardiés; J Bax; F Bengel; E Busemann Sokole; G Davies; M Dondi; L Edenbrandt; P Franken; A Kjaer; J Knuuti; M Lassmann; M Ljungberg; C Marcassa; P Y Marie; F McKiddie; M O'Connor; E Prvulovich; R Underwood; B van Eck-Smit
Journal:  Eur J Nucl Med Mol Imaging       Date:  2005-07       Impact factor: 9.236

Review 5.  Uses and limitations of positron emission tomography in clinical pharmacokinetics/dynamics (Part II).

Authors:  L L Ponto; J A Ponto
Journal:  Clin Pharmacokinet       Date:  1992-04       Impact factor: 6.447

Review 6.  Image-derived input function for brain PET studies: many challenges and few opportunities.

Authors:  Paolo Zanotti-Fregonara; Kewei Chen; Jeih-San Liow; Masahiro Fujita; Robert B Innis
Journal:  J Cereb Blood Flow Metab       Date:  2011-08-03       Impact factor: 6.200

7.  Different alterations in the insulin-stimulated glucose uptake in the athlete's heart and skeletal muscle.

Authors:  P Nuutila; M J Knuuti; O J Heinonen; U Ruotsalainen; M Teräs; J Bergman; O Solin; H Yki-Järvinen; L M Voipio-Pulkki; U Wegelius
Journal:  J Clin Invest       Date:  1994-05       Impact factor: 14.808

8.  Factors affecting myocardial 2-[F-18]fluoro-2-deoxy-D-glucose uptake in positron emission tomography studies of normal humans.

Authors:  Y Choi; R C Brunken; R A Hawkins; S C Huang; D B Buxton; C K Hoh; M E Phelps; H R Schelbert
Journal:  Eur J Nucl Med       Date:  1993-04

9.  Insulin resistance in liver cirrhosis. Positron-emission tomography scan analysis of skeletal muscle glucose metabolism.

Authors:  O Selberg; W Burchert; J vd Hoff; G J Meyer; H Hundeshagen; E Radoch; H J Balks; M J Müller
Journal:  J Clin Invest       Date:  1993-05       Impact factor: 14.808

10.  Reduced regional myocardial perfusion reserve is associated with impaired contractile performance in idiopathic dilated cardiomyopathy.

Authors:  R A Tio; R H J A Slart; R A de Boer; P A van der Vleuten; R M de Jong; L M van Wijk; T Willems; D D Lubbers; A A Voors; D J van Veldhuisen
Journal:  Neth Heart J       Date:  2009-12       Impact factor: 2.380
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.