Literature DB >> 20134468

Gene therapy activates EVI1, destabilizes chromosomes.

Cynthia E Dunbar, Andre Larochelle.   

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Year:  2010        PMID： 20134468     DOI： 10.1038/nm0210-163

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  12 in total

1.  Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells.

Authors:  Boris Calmels; Cole Ferguson; Mikko O Laukkanen; Rima Adler; Marion Faulhaber; Hyeoung-Joon Kim; Stephanie Sellers; Peiman Hematti; Manfred Schmidt; Christof von Kalle; Keiko Akagi; Robert E Donahue; Cynthia E Dunbar
Journal:  Blood       Date:  2005-06-02       Impact factor: 22.113

2.  Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy.

Authors:  Salima Hacein-Bey-Abina; Françoise Le Deist; Frédérique Carlier; Cécile Bouneaud; Christophe Hue; Jean-Pierre De Villartay; Adrian J Thrasher; Nicolas Wulffraat; Ricardo Sorensen; Sophie Dupuis-Girod; Alain Fischer; E Graham Davies; Wietse Kuis; Lilly Leiva; Marina Cavazzana-Calvo
Journal:  N Engl J Med       Date:  2002-04-18       Impact factor: 91.245

3.  Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

Authors:  Marion G Ott; Manfred Schmidt; Kerstin Schwarzwaelder; Stefan Stein; Ulrich Siler; Ulrike Koehl; Hanno Glimm; Klaus Kühlcke; Andrea Schilz; Hana Kunkel; Sonja Naundorf; Andrea Brinkmann; Annette Deichmann; Marlene Fischer; Claudia Ball; Ingo Pilz; Cynthia Dunbar; Yang Du; Nancy A Jenkins; Neal G Copeland; Ursula Lüthi; Moustapha Hassan; Adrian J Thrasher; Dieter Hoelzer; Christof von Kalle; Reinhard Seger; Manuel Grez
Journal:  Nat Med       Date:  2006-04-02       Impact factor: 53.440

4.  Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells.

Authors:  Yang Du; Nancy A Jenkins; Neal G Copeland
Journal:  Blood       Date:  2005-08-18       Impact factor: 22.113

5.  LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

Authors:  S Hacein-Bey-Abina; C Von Kalle; M Schmidt; M P McCormack; N Wulffraat; P Leboulch; A Lim; C S Osborne; R Pawliuk; E Morillon; R Sorensen; A Forster; P Fraser; J I Cohen; G de Saint Basile; I Alexander; U Wintergerst; T Frebourg; A Aurias; D Stoppa-Lyonnet; S Romana; I Radford-Weiss; F Gross; F Valensi; E Delabesse; E Macintyre; F Sigaux; J Soulier; L E Leiva; M Wissler; C Prinz; T H Rabbitts; F Le Deist; A Fischer; M Cavazzana-Calvo
Journal:  Science       Date:  2003-10-17       Impact factor: 47.728

6.  High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

Authors:  Sanne Lugthart; Ellen van Drunen; Yvette van Norden; Antoinette van Hoven; Claudia A J Erpelinck; Peter J M Valk; H Berna Beverloo; Bob Löwenberg; Ruud Delwel
Journal:  Blood       Date:  2008-02-13       Impact factor: 22.113

7.  A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.

Authors:  Dominik Spensberger; Ruud Delwel
Journal:  FEBS Lett       Date:  2008-07-11       Impact factor: 4.124

8.  Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector-transduced CD34+ cells.

Authors:  Yoo-Jin Kim; Yoon-Sang Kim; Andre Larochelle; Gabriel Renaud; Tyra G Wolfsberg; Rima Adler; Robert E Donahue; Peiman Hematti; Bum-Kee Hong; Jean Roayaei; Keiko Akagi; Janice M Riberdy; Arthur W Nienhuis; Cynthia E Dunbar; Derek A Persons
Journal:  Blood       Date:  2009-04-01       Impact factor: 22.113

9.  Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.

Authors:  Kerstin Cornils; Claudia Lange; Axel Schambach; Martijn H Brugman; Regine Nowak; Michael Lioznov; Christopher Baum; Boris Fehse
Journal:  Mol Ther       Date:  2008-11-11       Impact factor: 11.454

10.  Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration.

Authors:  Eugenio Montini; Daniela Cesana; Manfred Schmidt; Francesca Sanvito; Maurilio Ponzoni; Cynthia Bartholomae; Lucia Sergi Sergi; Fabrizio Benedicenti; Alessandro Ambrosi; Clelia Di Serio; Claudio Doglioni; Christof von Kalle; Luigi Naldini
Journal:  Nat Biotechnol       Date:  2006-05-28       Impact factor: 54.908
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  8 in total

Review 1.  Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models.

Authors:  Andre Larochelle; Cynthia E Dunbar
Journal:  Semin Hematol       Date:  2013-04       Impact factor: 3.851

2.  Genomic discovery of potent chromatin insulators for human gene therapy.

Authors:  Mingdong Liu; Matthew T Maurano; Hao Wang; Heyuan Qi; Chao-Zhong Song; Patrick A Navas; David W Emery; John A Stamatoyannopoulos; George Stamatoyannopoulos
Journal:  Nat Biotechnol       Date:  2015-01-12       Impact factor: 54.908

3.  Comprehensive characterization of genomic instability in pluripotent stem cells and their derived neuroprogenitor cell lines.

Authors:  Nestor Luis Lopez Corrales; Kristin Mrasek; Martin Voigt; Thomas Liehr; Nadezda Kosyakova
Journal:  Appl Transl Genom       Date:  2012-08-29

4.  EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

Authors:  Emilie A Bard-Chapeau; Jayantha Gunaratne; Pankaj Kumar; Belinda Q Chua; Julius Muller; Frederic A Bard; Walter Blackstock; Neal G Copeland; Nancy A Jenkins
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-15       Impact factor: 11.205

5.  Evaluation of biolistic gene transfer methods in vivo using non-invasive bioluminescent imaging techniques.

Authors:  Jixiang Xia; Angela Martinez; Henry Daniell; Steven N Ebert
Journal:  BMC Biotechnol       Date:  2011-06-02       Impact factor: 2.563

6.  Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice.

Authors:  Shanbao Cai; Haiyan Wang; Barbara Bailey; Jennifer R Hartwell; Jayne M Silver; Beth E Juliar; Anthony L Sinn; Arthur R Baluyut; Karen E Pollok
Journal:  Bone Marrow Res       Date:  2010-12-26

7.  Chronic Granulomatous Disease and Myelodysplastic Syndrome in a Patient with a Novel Mutation in CYBB.

Authors:  Bárbara C S Reis; Daniela P Cunha; Ana Paula S Bueno; Flavia A A Carvalho; Juliana Dutra; Fabiana V Mello; Maria Cecília Menks Ribeiro; Cristiane B Milito; Elaine Sobral da Costa; Zilton Vasconcelos
Journal:  Genes (Basel)       Date:  2021-09-23       Impact factor: 4.096

8.  Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza.

Authors:  Hanjun Zhao; Kelvin K W To; Hin Chu; Qiulu Ding; Xiaoyu Zhao; Cun Li; Huiping Shuai; Shuofeng Yuan; Jie Zhou; Kin-Hang Kok; Shibo Jiang; Kwok-Yung Yuen
Journal:  Nat Commun       Date:  2018-06-15       Impact factor: 14.919
  8 in total

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