Literature DB >> 20133481

Of mice and men: therapeutic mTOR inhibition in polycystic kidney disease.

York Pei.   

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Year:  2010        PMID： 20133481      PMCID： PMC4473250          DOI： 10.1681/ASN.2010010072

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN： 1046-6673            Impact factor:   10.121


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  15 in total

1.  Molecular pathogenesis of ADPKD: the polycystin complex gets complex.

Authors:  Albert C M Ong; Peter C Harris
Journal:  Kidney Int       Date:  2005-04       Impact factor: 10.612

2.  A "two-hit" model of cystogenesis in autosomal dominant polycystic kidney disease?

Authors:  Y Pei
Journal:  Trends Mol Med       Date:  2001-04       Impact factor: 11.951

3.  Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1.

Authors:  Jonathan M Shillingford; Klaus B Piontek; Gregory G Germino; Thomas Weimbs
Journal:  J Am Soc Nephrol       Date:  2010-01-14       Impact factor: 10.121

4.  Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease--a contiguous gene syndrome.

Authors:  P T Brook-Carter; B Peral; C J Ward; P Thompson; J Hughes; M M Maheshwar; M Nellist; V Gamble; P C Harris; J R Sampson
Journal:  Nat Genet       Date:  1994-12       Impact factor: 38.330

Review 5.  Polycystins and primary cilia: primers for cell cycle progression.

Authors:  Jing Zhou
Journal:  Annu Rev Physiol       Date:  2009       Impact factor: 19.318

6.  A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1.

Authors:  Klaus Piontek; Luis F Menezes; Miguel A Garcia-Gonzalez; David L Huso; Gregory G Germino
Journal:  Nat Med       Date:  2007-10-28       Impact factor: 53.440

7.  Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks.

Authors:  Xuewen Song; Valeria Di Giovanni; Ning He; Kairong Wang; Alistair Ingram; Norman D Rosenblum; York Pei
Journal:  Hum Mol Genet       Date:  2009-04-03       Impact factor: 6.150

Review 8.  Polycystic kidney disease.

Authors:  Peter C Harris; Vicente E Torres
Journal:  Annu Rev Med       Date:  2009       Impact factor: 13.739

9.  Sirolimus reduces polycystic liver volume in ADPKD patients.

Authors:  Qi Qian; Hui Du; Bernard F King; Sumedha Kumar; Patrick G Dean; Fernando G Cosio; Vicente E Torres
Journal:  J Am Soc Nephrol       Date:  2008-01-16       Impact factor: 10.121

10.  Pkd1 inactivation induced in adulthood produces focal cystic disease.

Authors:  Ayumi Takakura; Leah Contrino; Alexander W Beck; Jing Zhou
Journal:  J Am Soc Nephrol       Date:  2008-09-05       Impact factor: 10.121
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  2 in total

1.  c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.

Authors:  Shan Qin; Mary Taglienti; Lei Cai; Jing Zhou; Jordan A Kreidberg
Journal:  J Am Soc Nephrol       Date:  2012-06-07       Impact factor: 10.121

2.  RAPAMYCIN INCREASES LENGTH AND MECHANOSENSORY FUNCTION OF PRIMARY CILIA IN RENAL EPITHELIAL AND VASCULAR ENDOTHELIAL CELLS.

Authors:  Rinzhin T Sherpa; Kimberly F Atkinson; Viviana P Ferreira; Surya M Nauli
Journal:  Int Educ Res J       Date:  2016-12
  2 in total

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