Literature DB >> 2013321

The organization of the gene for the human cerebroside sulfate activator protein.

H Holtschmidt1, K Sandhoff, W Fürst, H Y Kwon, D Schnabel, K Suzuki.   

Abstract

The organization of 14 exons covering 97% of the cDNA sequence of human cerebroside sulfate activator protein precursor has been determined from two overlapping EMBL-4 human genomic clones extending over 17 kb. All exons and exon/intron splice junctions and five introns were sequenced. Exon 8 consists of only 9 bp and is involved in alternative splicing which generates three different mRNAs of cerebroside sulfate activator precursor.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 2013321     DOI： 10.1016/0014-5793(91)80308-p

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

1.  Cloning, expression and map assignment of chicken prosaposin.

Authors:  N Azuma; H C Seo; O Lie; Q Fu; R M Gould; M Hiraiwa; D W Burt; I R Paton; D R Morrice; J S O'Brien; Y Kishimoto
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

2.  A non-glycosylated and functionally deficient mutant (N215H) of the sphingolipid activator protein B (SAP-B) in a novel case of metachromatic leukodystrophy (MLD).

Authors:  D Wrobe; M Henseler; S Huettler; S I Pascual Pascual; A Chabas; K Sandhoff
Journal:  J Inherit Metab Dis       Date:  2000-02       Impact factor: 4.982

3.  [Glycolipids of the cell surface--biochemistry of their decomposition].

Authors:  K Sandhoff; T Kolter
Journal:  Naturwissenschaften       Date:  1995-09

Review 4.  The arylsulphatase A gene and molecular genetics of metachromatic leucodystrophy.

Authors:  M L Barth; A Fensom; A Harris
Journal:  J Med Genet       Date:  1994-09       Impact factor: 6.318

5.  Additional biochemical findings in a patient and fetal sibling with a genetic defect in the sphingolipid activator protein (SAP) precursor, prosaposin. Evidence for a deficiency in SAP-1 and for a normal lysosomal neuraminidase.

Authors:  B C Paton; B Schmid; B Kustermann-Kuhn; A Poulos; K Harzer
Journal:  Biochem J       Date:  1992-07-15       Impact factor: 3.857

6.  Methionine oxidation within the cerebroside-sulfate activator protein (CSAct or Saposin B).

Authors:  J P Whitelegge; B Penn; T To; J Johnson; A Waring; M Sherman; R L Stevens; C B Fluharty; K F Faull; A L Fluharty
Journal:  Protein Sci       Date:  2000-09       Impact factor: 6.725

7.  Prosaposin: promoter analysis and central-nervous-system-preferential elements for expression in vivo.

Authors:  Y Sun; P Jin; D P Witte; G A Grabowski
Journal:  Biochem J       Date:  2000-12-01       Impact factor: 3.857

8.  Analysis of a splice-site mutation in the sap-precursor gene of a patient with metachromatic leukodystrophy.

Authors:  M Henseler; A Klein; M Reber; M T Vanier; P Landrieu; K Sandhoff
Journal:  Am J Hum Genet       Date:  1996-01       Impact factor: 11.025

Review 9.  My journey into the world of sphingolipids and sphingolipidoses.

Authors:  Konrad Sandhoff
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2012       Impact factor: 3.493

10.  Interneurons secrete prosaposin, a neurotrophic factor, to attenuate kainic acid-induced neurotoxicity.

Authors:  Hiroaki Nabeka; Shouichiro Saito; Xuan Li; Tetsuya Shimokawa; Md Sakirul Islam Khan; Kimiko Yamamiya; Soichiro Kawabe; Takuya Doihara; Fumihiko Hamada; Naoto Kobayashi; Seiji Matsuda
Journal:  IBRO Rep       Date:  2017-08-22
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.