Literature DB >> 20129994

Should access to fertility treatment be determined by female body mass index?

S Pandey1, A Maheshwari, S Bhattacharya.   

Abstract

Resource allocation towards fertility treatment has been extensively debated in countries where fertility treatment is publicly-funded. Medical, social and ethical aspects have been evaluated prior to allocation of resources. Analysis of cost-effectiveness, risks and benefits and poor success rates have led to calls of restricting fertility treatment to obese women. In this debate article, we critically appraise the evidence underlying this issue and highlight the problems with such a policy. Poor success rate of treatment is unsubstantiated as there is insufficient evidence to link high body mass index (BMI) to reduction in live birth. Obstetric complications have a linear relationship with BMI but are significantly influenced by maternal age. The same is true for miscarriage rates which are influenced by the confounding factors of polycystic ovary syndrome and age. Studies have shown that the direct costs per live birth are no greater for overweight and obese women. With changing demographics over half the reproductive-age population is overweight or obese. Restricting fertility treatment on the grounds of BMI would cause stigmatization and lead to inequity, feelings of injustice and social tension as affluent women manage to bypass these draconian restrictions. Time lost and poor success of conventional weight loss strategies would jeopardize the chances of conception for many women.

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Year:  2010        PMID: 20129994     DOI: 10.1093/humrep/deq013

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  11 in total

1.  Body mass index and short-term weight change in relation to treatment outcomes in women undergoing assisted reproduction.

Authors:  Jorge E Chavarro; Shelley Ehrlich; Daniela S Colaci; Diane L Wright; Thomas L Toth; John C Petrozza; Russ Hauser
Journal:  Fertil Steril       Date:  2012-05-16       Impact factor: 7.329

2.  The LIFESTYLE study: costs and effects of a structured lifestyle program in overweight and obese subfertile women to reduce the need for fertility treatment and improve reproductive outcome. A randomised controlled trial.

Authors:  Meike A Q Mutsaerts; Henk Groen; Nancy C W ter Bogt; Johanna H T Bolster; Jolande A Land; Wanda J E Bemelmans; Walter K H Kuchenbecker; Peter G A Hompes; Nick S Macklon; Ronald P Stolk; Fulco van der Veen; Jacques W M Maas; Nicole F Klijn; Eugenie M Kaaijk; Gerrit J E Oosterhuis; Peter X J M Bouckaert; Jaap M Schierbeek; Yvonne M van Kasteren; Annemiek W Nap; Frank J Broekmans; Egbert A Brinkhuis; Carolien A M Koks; Jan M Burggraaff; Adrienne S Blankhart; Denise A M Perquin; Marie H Gerards; Robert J A B Mulder; Ed T C M Gondrie; Ben W J Mol; Annemieke Hoek
Journal:  BMC Womens Health       Date:  2010-06-25       Impact factor: 2.809

3.  Infertility patients' knowledge of the effects of obesity on reproductive health outcomes.

Authors:  Eden R Cardozo; Lisa M Neff; Maureen E Brocks; Geraldine E Ekpo; Tanaka J Dune; Randall B Barnes; Erica E Marsh
Journal:  Am J Obstet Gynecol       Date:  2012-08-16       Impact factor: 8.661

4.  Feasibility of a brief, intensive weight loss intervention to improve reproductive outcomes in obese, subfertile women: a pilot study.

Authors:  Amy Rothberg; Michael Lanham; John Randolph; Christine Fowler; Nicole Miller; Yolanda Smith
Journal:  Fertil Steril       Date:  2016-06-20       Impact factor: 7.329

Review 5.  Polycystic ovary syndrome: current status and future perspective.

Authors:  Erin K Barthelmess; Rajesh K Naz
Journal:  Front Biosci (Elite Ed)       Date:  2014-01-01

6.  Effect of weight status on pregnancy outcome in intra cytoplasmic sperm injection.

Authors:  Rehana Rehman; Zahir Hussain; Syeda Sadia Fatima
Journal:  Iran J Reprod Med       Date:  2013-09

7.  Irresponsibly Infertile? Obesity, Efficiency, and Exclusion from Treatment.

Authors:  Rebecca C H Brown
Journal:  Health Care Anal       Date:  2019-06

8.  Does body mass index impact assisted reproductive technology treatment outcomes in gestational carriers.

Authors:  Noga Fuchs Weizman; Miranda K Defer; Janice Montbriand; Julia M Pasquale; Adina Silver; Clifford L Librach
Journal:  Reprod Biol Endocrinol       Date:  2020-05-02       Impact factor: 5.211

9.  Efficacy of an Internet-Based Intervention to Promote a Healthy Lifestyle on the Reproductive Parameters of Overweight and Obese Women: Study Protocol for a Randomised Controlled Trial.

Authors:  Gemma Biviá-Roig; Ruth Blasco-Sanz; Ana Boldó-Roda; M Dolores Vara; Tamara Escrivá-Martínez; Rocío Herrero; Valentina Lucia La Rosa; Rosa M Baños; Juan Francisco Lisón
Journal:  Int J Environ Res Public Health       Date:  2020-11-10       Impact factor: 3.390

10.  Impact of Women Obesity and Obesity Severity on Live Birth Rate after In Vitro Fertilization.

Authors:  Cécile Brunet; Safa Aouinti; Fanchon Huguet; Valérie Macioce; Noémie Ranisavljevic; Anna Gala; Antoine Avignon; Thibault Mura; Ariane Sultan
Journal:  J Clin Med       Date:  2020-07-28       Impact factor: 4.241

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