Literature DB >> 20129204

Targeted therapies in osteoarthritis: a systematic review of the trials on www.clinicaltrials.gov.

Francis Berenbaum1.   

Abstract

A systematic review of the clinical trials in osteoarthritis registered on the public website of the Clinical Trials Data Bank at the National Institutes of Health (NIH) has been performed. Such a review should cover the majority of the ongoing or forthcoming trials in the disease. This review focusses on trials designed to test safety and/or efficacy of targeted therapies in osteoarthritis. Copyright 2009 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20129204     DOI： 10.1016/j.berh.2009.08.007

Source DB:  PubMed          Journal:  Best Pract Res Clin Rheumatol        ISSN： 1521-6942            Impact factor:   4.098


  9 in total

Review 1.  The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis.

Authors:  Jérémie Sellam; Francis Berenbaum
Journal:  Nat Rev Rheumatol       Date:  2010-10-05       Impact factor: 20.543

2.  Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-κB and JNK/p38 MAPK activation pathways.

Authors:  I-Ni Hsieh; Anita Shin-Yuan Chang; Che-Ming Teng; Chien-Chih Chen; Chia-Ron Yang
Journal:  J Biomed Sci       Date:  2011-05-06       Impact factor: 8.410

3.  Autologous processed plasma: cytokine profile and effects upon injection into healthy equine joints.

Authors:  Juliana J Moreira; Ana Paula L Moraes; Patrícia M Brossi; Thaís S L Machado; Yara M Michelacci; Cristina O Massoco; Raquel Y A Baccarin
Journal:  J Vet Sci       Date:  2014-09-30       Impact factor: 1.672

4.  Rationale, design and protocol of a longitudinal study assessing the effect of total knee arthroplasty on habitual physical activity and sedentary behavior in adults with osteoarthritis.

Authors:  Rebecca M Meiring; Emmanuel Frimpong; Lipalo Mokete; Jurek Pietrzak; Dick Van Der Jagt; Mohammed Tikly; Joanne A McVeigh
Journal:  BMC Musculoskelet Disord       Date:  2016-07-13       Impact factor: 2.362

5.  Self-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacerein.

Authors:  Amal Ahmed Eltobshi; Elham Abdelmonem Mohamed; Galal Mahmoud Abdelghani; Ahmed Talaat Nouh
Journal:  Int J Nanomedicine       Date:  2018-10-18

6.  Virtual monoenergetic images from photon-counting spectral computed tomography to assess knee osteoarthritis.

Authors:  Christine Chappard; Juan Abascal; Cécile Olivier; Salim Si-Mohamed; Loic Boussel; Jean Baptiste Piala; Philippe Douek; Francoise Peyrin
Journal:  Eur Radiol Exp       Date:  2022-02-22

7.  Diacerein protects against iodoacetate-induced osteoarthritis in the femorotibial joints of rats.

Authors:  Achint Jain; Royana Singh; Saurabh Singh; Sanjay Singh
Journal:  J Biomed Res       Date:  2015-06-28

8.  Randomised, controlled trial of avocado-soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study.

Authors:  Emmanuel Maheu; Christian Cadet; Marc Marty; Dominique Moyse; Isabelle Kerloch; Philippe Coste; Maxime Dougados; Bernard Mazières; Tim D Spector; Hafid Halhol; Jean-Marie Grouin; Michel Lequesne
Journal:  Ann Rheum Dis       Date:  2013-01-23       Impact factor: 19.103

9.  LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation.

Authors:  Hongfei Zhang; Jinglian Li; Weiguang Shao; Naipeng Shen
Journal:  BMC Musculoskelet Disord       Date:  2020-08-01       Impact factor: 2.362
  9 in total

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