Literature DB >> 20128387

[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].

Jie Hui1, Yun-Fei Gu, Xiao-Mei Wu, Zong-Cheng Zhu, Jian-Ping Song, Xiang-Jun Yang, Zhi-Hua Liu, Ting-Bo Jiang, Zu-Xiang Fagn, Wen-Ping Jiang.   

Abstract

OBJECTIVE: The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).
METHOD: Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.
RESULTS: A total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.
CONCLUSIONS: This newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.

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Year:  2009        PMID: 20128387

Source DB:  PubMed          Journal:  Zhonghua Xin Xue Guan Bing Za Zhi        ISSN: 0253-3758


  1 in total

1.  TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.

Authors:  Mohan Liu; James N Ingle; Brooke L Fridley; Aman U Buzdar; Mark E Robson; Michiaki Kubo; Liewei Wang; Anthony Batzler; Gregory D Jenkins; Tracy L Pietrzak; Erin E Carlson; Matthew P Goetz; Donald W Northfelt; Edith A Perez; Clark V Williard; Daniel J Schaid; Yusuke Nakamura; Richard M Weinshilboum
Journal:  Mol Endocrinol       Date:  2013-03-21
  1 in total

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