Literature DB >> 20128188

Effects of Gold laser on the avian chorioallantoic membrane.

Catherine J Rees1, Jacqueline Allen, Gregory N Postma, Peter C Belafsky.   

Abstract

OBJECTIVES: Office-based lasers have revolutionized the treatment of laryngeal disease. The 980-nm Gold laser is a device that may offer some practical advantages over other office lasers. The chick chorioallantoic membrane has been proposed as a model for predicting the effects of photoangiolytic lasers on vocal fold microvasculature. We sought to evaluate the effects of the Gold laser in this model.
METHODS: Vascular reactions in first-order vessels were determined for the Gold laser with both 0 degree straight and 30 degrees angled laser fibers. Vessels were treated at 15 W and a 500-ms pulse interval, with a 1-mm working distance. Pulse widths of 300 ms and 500 ms were evaluated. All vessels were treated until selective coagulation or vessel rupture.
RESULTS: We performed 60 trials on 30 embryos. The mean energy delivered was 33.7 J for the straight fiber and 51.2 J for the angled fiber. The laser achieved selective vessel coagulation without rupture in 100% (30 of 30) of straight fiber trials and in 100% (30 of 30) of angled fiber trials. In 6.7% (2 of 30) of straight fiber and 10% (3 of 30) of angled fiber trials, it caused minor injury to the surrounding albumin as indicated by white coagulum outside the vessel.
CONCLUSIONS: The Gold laser effectively coagulates small vessels without rupture at a working distance of 1 mm and settings of 15 W, 500-ms pulse interval, and 300- to 500-ms pulse width.

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Year:  2010        PMID: 20128188     DOI: 10.1177/000348941011900110

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  2 in total

Review 1.  The chicken chorioallantoic membrane model in biology, medicine and bioengineering.

Authors:  Patrycja Nowak-Sliwinska; Tatiana Segura; M Luisa Iruela-Arispe
Journal:  Angiogenesis       Date:  2014-08-20       Impact factor: 9.596

2.  Doppler optical coherence tomography for energy seal evaluation and comparison to visual evaluation.

Authors:  Andrew Marques; Robnier Reyes; Christopher R Pasarikovski; Chaoliang Chen; Joel Ramjist; Xijia Gu; Victor Yang
Journal:  J Biomed Opt       Date:  2020-03       Impact factor: 3.170

  2 in total

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