Literature DB >> 20127231

Pattern of drug use during the first trimester among Chinese women: data from a population-based cohort study.

Xiaoming Zhu1, Xiuyu Qi, Jiahu Hao, Zhaohui Huang, Zhihua Zhang, Xiuya Xing, Daijuan Cheng, Limin Xiao, Yuanyuan Xu, Peng Zhu, Fangbiao Tao.   

Abstract

AIM: To describe the pattern of drug use among Chinese women during the first trimester and to examine the impact of maternal diseases on the choice of drugs.
METHOD: This drug utilisation study of pregnant women was performed using data from the ABCD cohort study. A total of 4,290 women were enrolled in the analysis. Information was collected by self-completion questionnaire combined with the "Maternal health handbook".
RESULTS: Of the 4,290 women interviewed, 75.9% of women took at least one drug during the first trimester. Users took a mean number of 1.43 drugs. The most frequently used drugs were folic acid (65.2%), vitamins (14.6%), calcium (12.0%), minerals (11.1%), Chinese traditional patent medicine (CTPM; 10.1%) and anti-infectives (6.5%). Among the women having used CTPM, influenza/cold and threatened abortion were the most commonly reported indications. Logistic regression analysis of drug use (excluding nutritional and haematological drugs) shows that CTPM and Western medicine are both associated with the use of drugs for occasional diseases and against threatened abortion. Maternal chronic diseases were not associated with the use of CTPM.
CONCLUSION: This analysis of pregnant women showed that drugs were prescribed to most women, even when nutritional and haematological drugs were excluded. Our data reflect, except for drugs used for chronic diseases, a general reluctance among Chinese women to use Western medicine and resorting to CTPM during pregnancy.

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Year:  2010        PMID: 20127231     DOI: 10.1007/s00228-009-0781-x

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


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