| Literature DB >> 20122396 |
Abdelkader Essafi1, Nicholas D Hastie.
Abstract
Here, Hartkamp et al. (2010) identify WT1 as a novel bona fide substrate of the HtrA2/Omi mitochondrial protease and show that this reaction modulates WT1 antiapoptotic activity under cytotoxic stress. This supports an oncogenic function for WT1, with implications for novel chemotherapeutic avenues. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID： 20122396 DOI： 10.1016/j.molcel.2010.01.010
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970