| Literature DB >> 201214 |
R C Ostenson, B T Fields, C M Nolan.
Abstract
Polymyxin B and rifampin were given to 12 patients with multi-drug-resistant nosocomial Serratia marcescens infections. Eight cures were achieved; drug hepatotoxicity occurred once; one fatal suprainfection was encountered; and two patients died during therapy of causes related to severe underlying illnesses. Polymyxin B and rifampin were uniformly synergistic in vitro against the infecting strains and against 40 additional clinical isolates of S. marcescens.Entities:
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Year: 1977 PMID: 201214 PMCID: PMC429999 DOI: 10.1128/AAC.12.6.655
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191